Synthesis and aggregation behavior of multiresponsive double hydrophilic ABC miktoarm star terpolymer

Yanfeng Zhang; Hao Liu; Jinming Hu; Changhua Li; Shiyong Liu

doi:10.1002/marc.200800820

Synthesis and aggregation behavior of multiresponsive double hydrophilic ABC miktoarm star terpolymer

Yanfeng Zhang
, Hao Liu
, Jinming Hu
, Changhua Li
, Shiyong Liu

University of Science and Technology of China

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

We report the first example of the synthesis and the " schizophrenic" micellization behavior of a multi-responsive double hydrophilic ABC miktoarm star terpolymer. A well-defined miktoarm star terpolymer consisting of polyethylene glycol), poly(2-(diethylamino)ethyl methacrylate), and poly(N-isopropylacrylamide) arms, PEG(-b-PDEA)-b-PNIPAM, was synthesized via the combination of atom transfer radical polymerization (ATRP) and click reaction. Containing pH-responsive PDEA and thermo-responsive PNIPAM arms, this novel type of miktoarm star terpolymer molecularly dissolves in aqueous solution at acidic pH and room temperature, but supramolecularly self -into micelles at alkaline pH and room temperature, and PNIPAM-core micelles at acidic pH and elevated temperatures. Most importantly, both types of micellar aggregates possess wellsolvated hybrid coronas.

Original language	English
Pages (from-to)	941-947
Number of pages	7
Journal	Macromolecular Rapid Communications
Volume	30
Issue number	11
DOIs	https://doi.org/10.1002/marc.200800820
State	Published - 2 Jun 2009
Externally published	Yes

Keywords

Atom transfer radical polymerization (ATRP)
Click reaction
Double hydrophilic block copolymer
Self-organization
Stimuli-sensitive polymers

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10.1002/marc.200800820

Cite this

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title = "Synthesis and aggregation behavior of multiresponsive double hydrophilic ABC miktoarm star terpolymer",

abstract = "We report the first example of the synthesis and the {"} schizophrenic{"} micellization behavior of a multi-responsive double hydrophilic ABC miktoarm star terpolymer. A well-defined miktoarm star terpolymer consisting of polyethylene glycol), poly(2-(diethylamino)ethyl methacrylate), and poly(N-isopropylacrylamide) arms, PEG(-b-PDEA)-b-PNIPAM, was synthesized via the combination of atom transfer radical polymerization (ATRP) and click reaction. Containing pH-responsive PDEA and thermo-responsive PNIPAM arms, this novel type of miktoarm star terpolymer molecularly dissolves in aqueous solution at acidic pH and room temperature, but supramolecularly self -into micelles at alkaline pH and room temperature, and PNIPAM-core micelles at acidic pH and elevated temperatures. Most importantly, both types of micellar aggregates possess wellsolvated hybrid coronas.",

keywords = "Atom transfer radical polymerization (ATRP), Click reaction, Double hydrophilic block copolymer, Self-organization, Stimuli-sensitive polymers",

author = "Yanfeng Zhang and Hao Liu and Jinming Hu and Changhua Li and Shiyong Liu",

year = "2009",

month = jun,

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doi = "10.1002/marc.200800820",

language = "英语",

volume = "30",

pages = "941--947",

journal = "Macromolecular Rapid Communications",

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TY - JOUR

T1 - Synthesis and aggregation behavior of multiresponsive double hydrophilic ABC miktoarm star terpolymer

AU - Zhang, Yanfeng

AU - Liu, Hao

AU - Hu, Jinming

AU - Li, Changhua

AU - Liu, Shiyong

PY - 2009/6/2

Y1 - 2009/6/2

N2 - We report the first example of the synthesis and the " schizophrenic" micellization behavior of a multi-responsive double hydrophilic ABC miktoarm star terpolymer. A well-defined miktoarm star terpolymer consisting of polyethylene glycol), poly(2-(diethylamino)ethyl methacrylate), and poly(N-isopropylacrylamide) arms, PEG(-b-PDEA)-b-PNIPAM, was synthesized via the combination of atom transfer radical polymerization (ATRP) and click reaction. Containing pH-responsive PDEA and thermo-responsive PNIPAM arms, this novel type of miktoarm star terpolymer molecularly dissolves in aqueous solution at acidic pH and room temperature, but supramolecularly self -into micelles at alkaline pH and room temperature, and PNIPAM-core micelles at acidic pH and elevated temperatures. Most importantly, both types of micellar aggregates possess wellsolvated hybrid coronas.

AB - We report the first example of the synthesis and the " schizophrenic" micellization behavior of a multi-responsive double hydrophilic ABC miktoarm star terpolymer. A well-defined miktoarm star terpolymer consisting of polyethylene glycol), poly(2-(diethylamino)ethyl methacrylate), and poly(N-isopropylacrylamide) arms, PEG(-b-PDEA)-b-PNIPAM, was synthesized via the combination of atom transfer radical polymerization (ATRP) and click reaction. Containing pH-responsive PDEA and thermo-responsive PNIPAM arms, this novel type of miktoarm star terpolymer molecularly dissolves in aqueous solution at acidic pH and room temperature, but supramolecularly self -into micelles at alkaline pH and room temperature, and PNIPAM-core micelles at acidic pH and elevated temperatures. Most importantly, both types of micellar aggregates possess wellsolvated hybrid coronas.

KW - Atom transfer radical polymerization (ATRP)

KW - Click reaction

KW - Double hydrophilic block copolymer

KW - Self-organization

KW - Stimuli-sensitive polymers

UR - https://www.scopus.com/pages/publications/66749137569

U2 - 10.1002/marc.200800820

DO - 10.1002/marc.200800820

M3 - 文章

AN - SCOPUS:66749137569

SN - 1022-1336

VL - 30

SP - 941

EP - 947

JO - Macromolecular Rapid Communications

JF - Macromolecular Rapid Communications

IS - 11

ER -

Synthesis and aggregation behavior of multiresponsive double hydrophilic ABC miktoarm star terpolymer

Abstract

Keywords

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