Surface acoustic wave induced thermal lysis of red blood cells in microfluidic channel

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In this paper, we present a novel surface acoustic wave (SAW) method for continuous red blood cell lysis. Assisted by the SAWs, 95% cell lysis was achieved in the microfluidic channel. Through changing the supplied electrical signal, the effects of different parameters on lysing efficiency were studied. To further explore the lysis mechanism, different factors induced by SAWs were analyzed. This method provides a new approach for continuous cell lysis, which can be potentially integrated with biochips for DNA extraction to realize the high efficiency cell pretreatment system.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages2062-2064
Number of pages3
ISBN (Electronic)9780979806483
StatePublished - 2015
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 25 Oct 201529 Oct 2015

Publication series

NameMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Country/TerritoryKorea, Republic of
CityGyeongju
Period25/10/1529/10/15

Keywords

  • Cell lysis
  • Microfluidics
  • Surface acoustic wave
  • Thermal effect

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