Abstract
Objective: To investigate the mitochondrial DNA sequence polymorphisms in the Sala population from northwest China and to provide basic data for forensic purpose. Methods: Genomic DNA was extracted from the whole blood of 100 unrelated individuals of the Sala population. The sequence polymorphic locus was determined by direct sequencing. Results: 83 loci were observed in mtDNA np16 091-16 418 region, and 75 haplotypes were confirmed. The genetic diversity was estimated to be 0.991 2, and the random match probability was calculated to be 0.018 9. Conclusion: There are some particular polymorphic loci in the Sala population. The results suggest that there are different genetic structures between Chinese and other Asian population in mitochondrial DNA D-loop region; mitochondrial DNA sequence polymorphism np16 091-16 418 can be used as a genetic marker for forensic individual identification.
| Original language | English |
|---|---|
| Pages (from-to) | 213-216 |
| Number of pages | 4 |
| Journal | Journal of Xi'an Jiaotong University (Medical Sciences) |
| Volume | 25 |
| Issue number | 3 |
| State | Published - Jun 2004 |
Keywords
- D-loop region
- Sequence polymorphism
- mtDNA
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