Abstract
Objective: To study the expression of cadherins in different development stages of mouse tooth germ. Methods: We performed immunohistochemical staining after preparing specimens of different stages of the first molar developing tooth germ in mice. Results: The expression of cadherins was prominent in the inner enamel epithelium in bud, cap and bell stages. When the enamel and dentine matrices started developing, a strong staining reaction was evident in the ameloblasts and odontoblasts in mid time of bell stage. Conclusion: Cadherins may play a role in tooth morphogenesis. The results suggest that cadherins may contribute to the development of enamel and dentine matrices and mineralization process.
| Original language | English |
|---|---|
| Pages (from-to) | 297-299 |
| Number of pages | 3 |
| Journal | Journal of Xi'an Jiaotong University (Medical Sciences) |
| Volume | 24 |
| Issue number | 4 |
| State | Published - Aug 2003 |
| Externally published | Yes |
Keywords
- Cadherin
- Expression
- The development of tooth germ