Single-layer MoS2 nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy

Jianyu Han; Hongping Xia; Yafeng Wu; Shik Nie Kong; Amudha Deivasigamani; Rong Xu; Kam M. Hui; Yuejun Kang

doi:10.1039/c6nr00150e

Single-layer MoS₂ nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy

Jianyu Han
, Hongping Xia
, Yafeng Wu
, Shik Nie Kong
, Amudha Deivasigamani
, Rong Xu
, Kam M. Hui
, Yuejun Kang

Health Science Center

Nanyang Technological University
National Cancer Centre
Southwest University

Research output: Contribution to journal › Article › peer-review

97 Scopus citations

Abstract

A multifunctional nanostructure is prepared by covalently grafting upconversion nanoparticles (UCNPs) with chitosan functionalized MoS₂ (MoS₂-CS) and folic acid (FA) and then loading phthalocyanine (ZnPc) on the surface of MoS₂, which integrates photodynamic therapy (PDT) with photothermal therapy (PTT) and upconversion luminescence imaging into one system for enhanced antitumor efficiency.

Original language	English
Pages (from-to)	7861-7865
Number of pages	5
Journal	Nanoscale
Volume	8
Issue number	15
DOIs	https://doi.org/10.1039/c6nr00150e
State	Published - 21 Apr 2016

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1039/c6nr00150e

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title = "Single-layer MoS2 nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy",

abstract = "A multifunctional nanostructure is prepared by covalently grafting upconversion nanoparticles (UCNPs) with chitosan functionalized MoS2 (MoS2-CS) and folic acid (FA) and then loading phthalocyanine (ZnPc) on the surface of MoS2, which integrates photodynamic therapy (PDT) with photothermal therapy (PTT) and upconversion luminescence imaging into one system for enhanced antitumor efficiency.",

author = "Jianyu Han and Hongping Xia and Yafeng Wu and Kong, \{Shik Nie\} and Amudha Deivasigamani and Rong Xu and Hui, \{Kam M.\} and Yuejun Kang",

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doi = "10.1039/c6nr00150e",

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TY - JOUR

T1 - Single-layer MoS2 nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy

AU - Han, Jianyu

AU - Xia, Hongping

AU - Wu, Yafeng

AU - Kong, Shik Nie

AU - Deivasigamani, Amudha

AU - Xu, Rong

AU - Hui, Kam M.

AU - Kang, Yuejun

PY - 2016/4/21

Y1 - 2016/4/21

N2 - A multifunctional nanostructure is prepared by covalently grafting upconversion nanoparticles (UCNPs) with chitosan functionalized MoS2 (MoS2-CS) and folic acid (FA) and then loading phthalocyanine (ZnPc) on the surface of MoS2, which integrates photodynamic therapy (PDT) with photothermal therapy (PTT) and upconversion luminescence imaging into one system for enhanced antitumor efficiency.

AB - A multifunctional nanostructure is prepared by covalently grafting upconversion nanoparticles (UCNPs) with chitosan functionalized MoS2 (MoS2-CS) and folic acid (FA) and then loading phthalocyanine (ZnPc) on the surface of MoS2, which integrates photodynamic therapy (PDT) with photothermal therapy (PTT) and upconversion luminescence imaging into one system for enhanced antitumor efficiency.

UR - https://www.scopus.com/pages/publications/84964678960

U2 - 10.1039/c6nr00150e

DO - 10.1039/c6nr00150e

M3 - 文章

C2 - 27035265

AN - SCOPUS:84964678960

SN - 2040-3364

VL - 8

SP - 7861

EP - 7865

JO - Nanoscale

JF - Nanoscale

IS - 15

ER -

Single-layer MoS₂ nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy

Abstract

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