Abstract
In this study, a lab-on-chip (LOC) system is designed for the cell sensors to provide a high-efficient continuous analysis platform of acute toxicants in water environment. The chip is composed of three domains, including counter-flow micromixers, a T-junction droplet generator and time delay channels (TD-Cs). Water sample and bioluminescent bacterium Vibrio Fischeri (VF) are imported into the micromixers before that the droplet generator encapsulates them inside aqueous droplets separated by air. Air flow is the disperse medium, which can guarantee sufficient oxygen supply for the cells in droplets. The system shows high reliability and stability through numerical and experimental investigations.
| Original language | English |
|---|---|
| Title of host publication | Industrial Instrumentation and Control Systems II |
| Pages | 523-527 |
| Number of pages | 5 |
| DOIs | |
| State | Published - 2013 |
| Externally published | Yes |
| Event | 2013 2nd International Conference on Measurement, Instrumentation and Automation, ICMIA 2013 - Guilin, China Duration: 23 Apr 2013 → 24 Apr 2013 |
Publication series
| Name | Applied Mechanics and Materials |
|---|---|
| Volume | 336-338 |
| ISSN (Print) | 1660-9336 |
| ISSN (Electronic) | 1662-7482 |
Conference
| Conference | 2013 2nd International Conference on Measurement, Instrumentation and Automation, ICMIA 2013 |
|---|---|
| Country/Territory | China |
| City | Guilin |
| Period | 23/04/13 → 24/04/13 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 12 Responsible Consumption and Production
Keywords
- Cell-based sensor
- Digital microfluidic
- Micro-mixer
- Two-phase flow simulation
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