@inproceedings{89895b7e68444d0a9690a504c22247b3,
title = "Simulation and analysis of bacterial particle transportation in urinary tract with urethral calculus",
abstract = "The transportation and distribution of living bacteria particles were analyzed in a computational fluid model with the mobile phase of human urine, which resembles the pathogenesis of bacterial urine tract infections with complications of urethral calculi. Interrelated processes contributing to the mass transport and bacteria growth in the urine flow were evaluated. The two-dimensional model was also solved computationally. The results reflected that a urethral calculus could bring about the backward dispersal of bacteriuria in the case of urine tract infection. Furthermore, the shape of urethral stone is an important factor in the biofilm development on its surface. We also designed the conceptual experimental system for in-vitro simulation and further verification, composed of a cell-based lab-on-A-chip and the photomultiplier-Tube (PMT)-based bioluminescent detection module.",
keywords = "Lab on a chip, Medical simulation, Microfluidic device, Urethral calculus, Urinary tract infection",
author = "Xinyan Zhao and Kristin Imenes and Frank Karlsen and Tao Dong",
note = "Publisher Copyright: {\textcopyright} 2015 IEEE.; 11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015 ; Conference date: 22-10-2015 Through 24-10-2015",
year = "2015",
month = dec,
day = "4",
doi = "10.1109/BioCAS.2015.7348389",
language = "英语",
series = "IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
booktitle = "IEEE Biomedical Circuits and Systems Conference",
}