Simple precision creation of digitally specified, spatially heterogeneous, engineered tissue architectures

Umut Atakan Gurkan; Yantao Fan; Feng Xu; Burcu Erkmen; Emel Sokullu Urkac; Gunes Parlakgul; Jacob Bernstein; Wangli Xing; Edward S. Boyden; Utkan Demirci

doi:10.1002/adma.201203261

Simple precision creation of digitally specified, spatially heterogeneous, engineered tissue architectures

Umut Atakan Gurkan
, Yantao Fan
, Feng Xu
, Burcu Erkmen
, Emel Sokullu Urkac
, Gunes Parlakgul
, Jacob Bernstein
, Wangli Xing
, Edward S. Boyden
, Utkan Demirci

Harvard University
Massachusetts Institute of Technology
Tsinghua University
Harvard-Massachusetts Institutes of Technology Health Sciences and Technology

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Complex architectures of integrated circuits are achieved through multiple layer photolithography, which has empowered the semiconductor industry. We adapt this philosophy for tissue engineering with a versatile, scalable, and generalizable microfabrication approach to create engineered tissue architectures composed of digitally specifiable building blocks, each with tuned structural, cellular, and compositional features.

Original language	English
Pages (from-to)	1192-1198
Number of pages	7
Journal	Advanced Materials
Volume	25
Issue number	8
DOIs	https://doi.org/10.1002/adma.201203261
State	Published - 25 Feb 2013
Externally published	Yes

Keywords

advanced manufacturing
biofabrication
biomanufacturing
brain engineering
neural engineering
three-dimensional microfabrication
tissue engineering

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10.1002/adma.201203261

Cite this

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AU - Gurkan, Umut Atakan

AU - Fan, Yantao

AU - Xu, Feng

AU - Erkmen, Burcu

AU - Urkac, Emel Sokullu

AU - Parlakgul, Gunes

AU - Bernstein, Jacob

AU - Xing, Wangli

AU - Boyden, Edward S.

AU - Demirci, Utkan

PY - 2013/2/25

Y1 - 2013/2/25

N2 - Complex architectures of integrated circuits are achieved through multiple layer photolithography, which has empowered the semiconductor industry. We adapt this philosophy for tissue engineering with a versatile, scalable, and generalizable microfabrication approach to create engineered tissue architectures composed of digitally specifiable building blocks, each with tuned structural, cellular, and compositional features.

AB - Complex architectures of integrated circuits are achieved through multiple layer photolithography, which has empowered the semiconductor industry. We adapt this philosophy for tissue engineering with a versatile, scalable, and generalizable microfabrication approach to create engineered tissue architectures composed of digitally specifiable building blocks, each with tuned structural, cellular, and compositional features.

KW - advanced manufacturing

KW - biofabrication

KW - biomanufacturing

KW - brain engineering

KW - neural engineering

KW - three-dimensional microfabrication

KW - tissue engineering

UR - https://www.scopus.com/pages/publications/84874051026

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DO - 10.1002/adma.201203261

M3 - 文章

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JO - Advanced Materials

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ER -

Simple precision creation of digitally specified, spatially heterogeneous, engineered tissue architectures

Abstract

Keywords

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