Abstract
Context: Omentin-1, an adipokine secreted from visceral adipose tissue, has been reported to be associated with coronary artery disease (CAD) and metabolic disorders. Objective: To clarify the relationship between serum omentin-1 levels and the presence and severity of CAD in patients with metabolic syndrome (MetS). Methods: We measured serum omentin-1 levels in 175 consecutive patients with MetS and in 46 controls. Results: Serum omentin-1 levels are inversely associated with the presence and angiographic severity of CAD in MetS patients. Conclusions: Serum omentin-1 might be a potential biomarker to predict the development and progression of CAD in MetS patients.
| Original language | English |
|---|---|
| Pages (from-to) | 657-662 |
| Number of pages | 6 |
| Journal | Biomarkers |
| Volume | 16 |
| Issue number | 8 |
| DOIs | |
| State | Published - Dec 2011 |
| Externally published | Yes |
Keywords
- Adipokines
- Biomarker
- Cardiometabolic syndrome
- Coronary atherosclerosis index
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