Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

Dan Liu; Chunfang Li; Pu Huang; Jing Fu; Xin Dong; Yunhui Tang; Xuelan Li; Qi Chen

doi:10.1080/10641955.2020.1761377

Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

Dan Liu
, Chunfang Li
, Pu Huang
, Jing Fu
, Xin Dong
, Yunhui Tang
, Xuelan Li
, Qi Chen

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Objective: To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods: Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results: Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion: UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.

Original language	English
Pages (from-to)	260-266
Number of pages	7
Journal	Hypertension in Pregnancy
Volume	39
Issue number	3
DOIs	https://doi.org/10.1080/10641955.2020.1761377
State	Published - 2 Jul 2020
Externally published	Yes

Keywords

Severe preeclampsia
immediate delivery
prolongation
renal function
uric acid

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10.1080/10641955.2020.1761377

Cite this

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abstract = "Objective: To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods: Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results: Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion: UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.",

keywords = "Severe preeclampsia, immediate delivery, prolongation, renal function, uric acid",

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T1 - Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

AU - Liu, Dan

AU - Li, Chunfang

AU - Huang, Pu

AU - Fu, Jing

AU - Dong, Xin

AU - Tang, Yunhui

AU - Li, Xuelan

AU - Chen, Qi

PY - 2020/7/2

Y1 - 2020/7/2

N2 - Objective: To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods: Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results: Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion: UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.

AB - Objective: To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods: Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results: Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion: UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.

KW - Severe preeclampsia

KW - immediate delivery

KW - prolongation

KW - renal function

KW - uric acid

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DO - 10.1080/10641955.2020.1761377

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AN - SCOPUS:85084264489

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IS - 3

ER -

Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

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