Sequential Dynamic Fluorescence Switching Driven by Oxa-/Thiol-Michael Conjugate Addition-Elimination Reactions

Xiangkun Si; Xiaolong Sun

doi:10.1021/acs.orglett.5c01643

Sequential Dynamic Fluorescence Switching Driven by Oxa-/Thiol-Michael Conjugate Addition-Elimination Reactions

Xiangkun Si
, Xiaolong Sun

School of Life Science and Technology (SLST)

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

Abstract

A dynamic molecular system undergoing sequential reconfiguration and multi-state fluorescence switching via intramolecular oxa/thiol-Michael conjugate addition-elimination reactions is reported. Triggered sequentially by chemical, solvent, and most importantly pH stimuli, the controlled progression through distinct molecular states was monitored by ratiometric absorption/fluorescence and NMR spectroscopy. This stimulus-controlled fluorescence switching demonstrates utility for real-time monitoring of processes, like chemically induced polymer degradation.

Original language	English
Pages (from-to)	6630-6634
Number of pages	5
Journal	Organic Letters
Volume	27
Issue number	25
DOIs	https://doi.org/10.1021/acs.orglett.5c01643
State	Published - 27 Jun 2025

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10.1021/acs.orglett.5c01643

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title = "Sequential Dynamic Fluorescence Switching Driven by Oxa-/Thiol-Michael Conjugate Addition-Elimination Reactions",

abstract = "A dynamic molecular system undergoing sequential reconfiguration and multi-state fluorescence switching via intramolecular oxa/thiol-Michael conjugate addition-elimination reactions is reported. Triggered sequentially by chemical, solvent, and most importantly pH stimuli, the controlled progression through distinct molecular states was monitored by ratiometric absorption/fluorescence and NMR spectroscopy. This stimulus-controlled fluorescence switching demonstrates utility for real-time monitoring of processes, like chemically induced polymer degradation.",

author = "Xiangkun Si and Xiaolong Sun",

note = "Publisher Copyright: {\textcopyright} 2025 American Chemical Society.",

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doi = "10.1021/acs.orglett.5c01643",

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AU - Sun, Xiaolong

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Y1 - 2025/6/27

N2 - A dynamic molecular system undergoing sequential reconfiguration and multi-state fluorescence switching via intramolecular oxa/thiol-Michael conjugate addition-elimination reactions is reported. Triggered sequentially by chemical, solvent, and most importantly pH stimuli, the controlled progression through distinct molecular states was monitored by ratiometric absorption/fluorescence and NMR spectroscopy. This stimulus-controlled fluorescence switching demonstrates utility for real-time monitoring of processes, like chemically induced polymer degradation.

AB - A dynamic molecular system undergoing sequential reconfiguration and multi-state fluorescence switching via intramolecular oxa/thiol-Michael conjugate addition-elimination reactions is reported. Triggered sequentially by chemical, solvent, and most importantly pH stimuli, the controlled progression through distinct molecular states was monitored by ratiometric absorption/fluorescence and NMR spectroscopy. This stimulus-controlled fluorescence switching demonstrates utility for real-time monitoring of processes, like chemically induced polymer degradation.

UR - https://www.scopus.com/pages/publications/105008473299

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DO - 10.1021/acs.orglett.5c01643

M3 - 文章

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AN - SCOPUS:105008473299

SN - 1523-7060

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EP - 6634

JO - Organic Letters

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IS - 25

ER -

Sequential Dynamic Fluorescence Switching Driven by Oxa-/Thiol-Michael Conjugate Addition-Elimination Reactions

Abstract

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