Abstract
High radiation dose during x-ray computed tomography (CT) examinations can increase the risk of cancer and has become major concerns to patient. Accordingly, minimizing the radiation exposure without sacrificing image quality is a meaningful research topic. In this work, with the aim to reduce radiation during data acquisition, we propose a penalized weighted least-squares (PWLS) scheme to retain the image quality by incorporating a total generalized variation (TGV) regularization, which is referred to as "PWLS-TGV". Specifically, the TGV regularization utilizes second-order derivatives of the desired image with imposing some higher order smoothness in regions away from the edges and the weighted leastsquares term considers a data-dependent variance estimation serving for improvement of image reconstruction from low-dose CT measurement. Subsequently, an alternating minimization algorithm was adopted to optimize the associative objective function. The experimental results on digital phantom and real patient data show that the present PWLS-TGV method can achieve significant gains over the existing similar methods in noise and artifacts suppression.
| Original language | English |
|---|---|
| Title of host publication | 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 173-176 |
| Number of pages | 4 |
| ISBN (Electronic) | 9781467319591 |
| DOIs | |
| State | Published - 29 Jul 2014 |
| Externally published | Yes |
| Event | 11th IEEE International Symposium on Biomedical Imaging, ISBI 2014 - Beijing, China Duration: 29 Apr 2014 → 2 May 2014 |
Publication series
| Name | 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014 |
|---|
Conference
| Conference | 11th IEEE International Symposium on Biomedical Imaging, ISBI 2014 |
|---|---|
| Country/Territory | China |
| City | Beijing |
| Period | 29/04/14 → 2/05/14 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
Keywords
- CT
- Penalized weighted least-squares
- Total generalized variation
- Total variation
Fingerprint
Dive into the research topics of 'Second order total generalized variation for low-dose computed tomography image reconstruction'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver