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Second order total generalized variation for low-dose computed tomography image reconstruction

  • Shanzhou Niu
  • , Jianhua Ma
  • , Jing Huang
  • , Zhaoying Bian
  • , Zhengrong Liang
  • , Wufan Chen
  • Southern Medical University
  • Stony Brook University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

High radiation dose during x-ray computed tomography (CT) examinations can increase the risk of cancer and has become major concerns to patient. Accordingly, minimizing the radiation exposure without sacrificing image quality is a meaningful research topic. In this work, with the aim to reduce radiation during data acquisition, we propose a penalized weighted least-squares (PWLS) scheme to retain the image quality by incorporating a total generalized variation (TGV) regularization, which is referred to as "PWLS-TGV". Specifically, the TGV regularization utilizes second-order derivatives of the desired image with imposing some higher order smoothness in regions away from the edges and the weighted leastsquares term considers a data-dependent variance estimation serving for improvement of image reconstruction from low-dose CT measurement. Subsequently, an alternating minimization algorithm was adopted to optimize the associative objective function. The experimental results on digital phantom and real patient data show that the present PWLS-TGV method can achieve significant gains over the existing similar methods in noise and artifacts suppression.

Original languageEnglish
Title of host publication2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages173-176
Number of pages4
ISBN (Electronic)9781467319591
DOIs
StatePublished - 29 Jul 2014
Externally publishedYes
Event11th IEEE International Symposium on Biomedical Imaging, ISBI 2014 - Beijing, China
Duration: 29 Apr 20142 May 2014

Publication series

Name2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014

Conference

Conference11th IEEE International Symposium on Biomedical Imaging, ISBI 2014
Country/TerritoryChina
CityBeijing
Period29/04/142/05/14

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • CT
  • Penalized weighted least-squares
  • Total generalized variation
  • Total variation

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