SAW assisted blood/plasma separation in microchannel with constriction-expansion transition

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Abstract

A surface acoustic wave (SAW) based microfluidic device for human blood plasma separation has been proposed and experimentally demonstrated. The microchannel consists of a constriction-expansion section and a bifurcation channel. The effect of constriction-expansion transition on the blood separation has been investigated with and without SAW. An acoustic power of 20.43 dBm is found enough for plasma isolation from 50× diluted human blood at a flow rate of 0.006μL/min. Higher acoustic power is required for the blood separation at higher flow rate. A diagram of combined working conditions is obtained for guiding the successful blood/plasma separation in the microfluidic chip of given design.

Original languageEnglish
Title of host publication2015 IEEE 10th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages86-89
Number of pages4
ISBN (Electronic)9781467366953
DOIs
StatePublished - 1 Jul 2015
Event10th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2015 - Xi'an, China
Duration: 7 Apr 201511 Apr 2015

Publication series

Name2015 IEEE 10th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2015

Conference

Conference10th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2015
Country/TerritoryChina
CityXi'an
Period7/04/1511/04/15

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