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Role of AMPK in pulmonary diseases

  • Xi'an Jiaotong University

Research output: Contribution to journalReview articlepeer-review

Abstract

AMPK is an important protein kinase, which controls/regulates the activity of energy metabolism in human body. Recent study has found that AMPK plays a critical role in the pathophysiological process of a variety of diseases. In recent years, the relationship between AMPK and pulmonary diseases has aroused extensive attention. Studies suggest that AMPK has a potential role in the treatment of pulmonary diseases such as lung cancer, asthma, acute lung injury, pulmonary hypertension and cystic fibrosis. This review summarizes the biological characteristics of AMPK and its potential therapeutic effect on such diseases.

Original languageEnglish
Pages (from-to)460-463
Number of pages4
JournalChinese Pharmacological Bulletin
Volume29
Issue number4
DOIs
StatePublished - Apr 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • AMPK
  • Asthma
  • Lung cancer
  • PAH
  • Structure and function
  • Therapeutic effect

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