Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus

Haitao Zhu; Xiaoge Zhang; Yayi He; Liang Yu; Yi Lü; Kaili Pan; Bo Wang; Guoqiang Chen

doi:10.7507/1002-1892.201707049

Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus

Haitao Zhu
, Xiaoge Zhang
, Yayi He
, Liang Yu
, Yi Lü
, Kaili Pan
, Bo Wang
, Guoqiang Chen

Health Science Center

Xi'an Jiaotong University
Northwest Women’s and Children’s Hospital

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

目的: 综述糖尿病胰岛替代治疗的供体细胞来源及选择的研究进展。.

方法: 查阅近年来国内外关于糖尿病胰岛替代治疗及供体细胞来源的相关文献，进行总结分析。.

结果: 供体来源短缺仍是胰岛移植（pancreatic islet transplantation，PIT）面临的主要难题。目前，除同种异体/自体供胰外，异种（猪）胰岛、干细胞诱导胰岛及胰岛细胞株制备和应用等方面也取得了重要进展，潜在扩大了可植入细胞来源。.

结论: 充足、合适的供体细胞来源是临床广泛开展 PIT 治疗 1 型糖尿病（type 1 diabetes mellitus，T1DM）的前提。社会捐赠体系的完善，免疫耐受诱导、基因与生物工程等技术的发展有望解决供体细胞短缺问题，并为临床细胞替代治疗 T1DM 奠定了基础。.

Original language	English
Pages (from-to)	104-111
Number of pages	8
Journal	Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
Volume	32
Issue number	1
DOIs	https://doi.org/10.7507/1002-1892.201707049
State	Published - 1 Jan 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Islet transplantation
donator
stem cells
type 1 diabetes mellitus
xenotransplantation

Access to Document

10.7507/1002-1892.201707049

Cite this

Zhu, H., Zhang, X., He, Y., Yu, L., Lü, Y., Pan, K., Wang, B., & Chen, G. (2018). Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 32(1), 104-111. https://doi.org/10.7507/1002-1892.201707049

@article{37694dbb73044104bfc03863cd4b23c3,

title = "Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus",

abstract = "目的: 综述糖尿病胰岛替代治疗的供体细胞来源及选择的研究进展。.方法: 查阅近年来国内外关于糖尿病胰岛替代治疗及供体细胞来源的相关文献，进行总结分析。.结果: 供体来源短缺仍是胰岛移植（pancreatic islet transplantation，PIT）面临的主要难题。目前，除同种异体/自体供胰外，异种（猪）胰岛、干细胞诱导胰岛及胰岛细胞株制备和应用等方面也取得了重要进展，潜在扩大了可植入细胞来源。.结论: 充足、合适的供体细胞来源是临床广泛开展 PIT 治疗 1 型糖尿病（type 1 diabetes mellitus，T1DM）的前提。社会捐赠体系的完善，免疫耐受诱导、基因与生物工程等技术的发展有望解决供体细胞短缺问题，并为临床细胞替代治疗 T1DM 奠定了基础。.",

keywords = "Islet transplantation, donator, stem cells, type 1 diabetes mellitus, xenotransplantation",

author = "Haitao Zhu and Xiaoge Zhang and Yayi He and Liang Yu and Yi L{\"u} and Kaili Pan and Bo Wang and Guoqiang Chen",

year = "2018",

month = jan,

day = "1",

doi = "10.7507/1002-1892.201707049",

language = "英语",

volume = "32",

pages = "104--111",

journal = "Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery",

issn = "1002-1892",

publisher = "West China University of Medical Science",

number = "1",

}

Zhu, H, Zhang, X, He, Y, Yu, L, Lü, Y, Pan, K, Wang, B & Chen, G 2018, 'Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus', Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, vol. 32, no. 1, pp. 104-111. https://doi.org/10.7507/1002-1892.201707049

Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus. / Zhu, Haitao; Zhang, Xiaoge; He, Yayi et al.
In: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, Vol. 32, No. 1, 01.01.2018, p. 104-111.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus

AU - Zhu, Haitao

AU - Zhang, Xiaoge

AU - He, Yayi

AU - Yu, Liang

AU - Lü, Yi

AU - Pan, Kaili

AU - Wang, Bo

AU - Chen, Guoqiang

PY - 2018/1/1

Y1 - 2018/1/1

N2 - 目的: 综述糖尿病胰岛替代治疗的供体细胞来源及选择的研究进展。.方法: 查阅近年来国内外关于糖尿病胰岛替代治疗及供体细胞来源的相关文献，进行总结分析。.结果: 供体来源短缺仍是胰岛移植（pancreatic islet transplantation，PIT）面临的主要难题。目前，除同种异体/自体供胰外，异种（猪）胰岛、干细胞诱导胰岛及胰岛细胞株制备和应用等方面也取得了重要进展，潜在扩大了可植入细胞来源。.结论: 充足、合适的供体细胞来源是临床广泛开展 PIT 治疗 1 型糖尿病（type 1 diabetes mellitus，T1DM）的前提。社会捐赠体系的完善，免疫耐受诱导、基因与生物工程等技术的发展有望解决供体细胞短缺问题，并为临床细胞替代治疗 T1DM 奠定了基础。.

AB - 目的: 综述糖尿病胰岛替代治疗的供体细胞来源及选择的研究进展。.方法: 查阅近年来国内外关于糖尿病胰岛替代治疗及供体细胞来源的相关文献，进行总结分析。.结果: 供体来源短缺仍是胰岛移植（pancreatic islet transplantation，PIT）面临的主要难题。目前，除同种异体/自体供胰外，异种（猪）胰岛、干细胞诱导胰岛及胰岛细胞株制备和应用等方面也取得了重要进展，潜在扩大了可植入细胞来源。.结论: 充足、合适的供体细胞来源是临床广泛开展 PIT 治疗 1 型糖尿病（type 1 diabetes mellitus，T1DM）的前提。社会捐赠体系的完善，免疫耐受诱导、基因与生物工程等技术的发展有望解决供体细胞短缺问题，并为临床细胞替代治疗 T1DM 奠定了基础。.

KW - Islet transplantation

KW - donator

KW - stem cells

KW - type 1 diabetes mellitus

KW - xenotransplantation

UR - https://www.scopus.com/pages/publications/85054438811

U2 - 10.7507/1002-1892.201707049

DO - 10.7507/1002-1892.201707049

M3 - 文献综述

C2 - 29806374

AN - SCOPUS:85054438811

SN - 1002-1892

VL - 32

SP - 104

EP - 111

JO - Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery

JF - Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery

IS - 1

ER -

Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus

Abstract

UN SDGs

Keywords

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