Relationship between the nonlocal effect and lagging behavior in bioheat transfer

Lots of generalized heat conduction models have been developed in recent decades, such as local thermal nonequilibrium model, phase lagging model, and nonlocal heat conduction model. But no attempt was made to prove which model is better (or worse) than others, or whether there is a certain relationship between these different models. With this inspiration, we establish the nonlocal bioheat transfer equations with lagging time, and the two and three-temperature bioheat transfer equations with considering all the carrier's heat conduction effect are also constructed. Comparing the two (or three)-temperature equation model with the nonlocal bioheat transfer models with lagging time, one may obtain: the lagging time of temperature gradient τt and the nonlocal characteristic length λq in the space derivative items of heat flux have the same effect on heat transfer; when the heat transport occur among N energy carriers with considering the conduction effects of all carries, the heat transfer processes are dependent upon the high-order effect of τqN-1, τtN-1 and λt(2N-1) in nonlocal dual phase lag bioheat transfer model. This phenomenon is very important for biological and medical systems where numerous carriers may exist on the cellular level.