Abstract
Objective: To investigate the relation of pelvic three-dimensional conformal radiotherapy (3D-CRT) target with rectal dose distribution and irradiation volume in cervical cancer. Methods: In 45 patients with cervical cancer ( IIa- IIIb) treated in our department from September to December 2006, we compared rectal dose distribution in different treatment plans, conventional radiation, 4-field box radiation, 4-field oblique radiation and 5-field radiation, and studied the relationship between rectal irradiation volume and dose in the target area. Results: Compared with that of the other models, the dose distribution of CTV in 3D-CRT was relatively poor although it could satisfy the demand of treatment; dose distribution of D90, D80 and D50 in the radiated rectum differed significantly (P<0.05), but not D30. In the 4-field box model, the irradiation dose had a reverse correlation with the volume received by the rectum. Conclusion: Conformal radiotherapy for cervical cancer can decrease the dose and volume of irradiation received by the rectum.
| Original language | English |
|---|---|
| Pages (from-to) | 358-361+377 |
| Journal | Journal of Xi'an Jiaotong University (Medical Sciences) |
| Volume | 31 |
| Issue number | 3 |
| State | Published - May 2010 |
Keywords
- Cervical cancer
- Conformal radiotherapy
- Dose distribution
- Rectum
- Target
