Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process

Yu Zhou; Yalei Jiang; Lanqiong Zhang; Yukang Li; Ying Hao; Pei Zhou; Zhi Wang; Youming Zhang; Jen Shyang Ni; Yanzi Xu; Lingjie Meng; Dongfeng Dang

doi:10.1039/d5cc04640h

Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process

Yu Zhou
, Yalei Jiang
, Lanqiong Zhang
, Yukang Li
, Ying Hao
, Pei Zhou
, Zhi Wang
, Youming Zhang
, Jen Shyang Ni
, Yanzi Xu
, Lingjie Meng
, Dongfeng Dang

School of Chemistry

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Precise monitoring of cancer treatment at the subcellular level remains a critical challenge. Therefore, a lysosome-specific AIE nanoprobe integrating stimulated emission depletion (STED) imaging and photodynamic therapy is reported here. The probe enables real-time visualization of lysosomal dynamics and reactive oxygen species (ROS)-mediated apoptosis, offering a powerful platform for high-resolution imaging-guided cancer diagnosis and treatment.

Original language	English
Pages (from-to)	568-571
Number of pages	4
Journal	Chemical Communications
Volume	62
Issue number	2
DOIs	https://doi.org/10.1039/d5cc04640h
State	Published - 8 Jan 2026

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1039/d5cc04640h

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title = "Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process",

abstract = "Precise monitoring of cancer treatment at the subcellular level remains a critical challenge. Therefore, a lysosome-specific AIE nanoprobe integrating stimulated emission depletion (STED) imaging and photodynamic therapy is reported here. The probe enables real-time visualization of lysosomal dynamics and reactive oxygen species (ROS)-mediated apoptosis, offering a powerful platform for high-resolution imaging-guided cancer diagnosis and treatment.",

author = "Yu Zhou and Yalei Jiang and Lanqiong Zhang and Yukang Li and Ying Hao and Pei Zhou and Zhi Wang and Youming Zhang and Ni, \{Jen Shyang\} and Yanzi Xu and Lingjie Meng and Dongfeng Dang",

note = "Publisher Copyright: This journal is {\textcopyright} The Royal Society of Chemistry, 2026",

year = "2026",

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day = "8",

doi = "10.1039/d5cc04640h",

language = "英语",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process

AU - Zhou, Yu

AU - Jiang, Yalei

AU - Zhang, Lanqiong

AU - Li, Yukang

AU - Hao, Ying

AU - Zhou, Pei

AU - Wang, Zhi

AU - Zhang, Youming

AU - Ni, Jen Shyang

AU - Xu, Yanzi

AU - Meng, Lingjie

AU - Dang, Dongfeng

PY - 2026/1/8

Y1 - 2026/1/8

N2 - Precise monitoring of cancer treatment at the subcellular level remains a critical challenge. Therefore, a lysosome-specific AIE nanoprobe integrating stimulated emission depletion (STED) imaging and photodynamic therapy is reported here. The probe enables real-time visualization of lysosomal dynamics and reactive oxygen species (ROS)-mediated apoptosis, offering a powerful platform for high-resolution imaging-guided cancer diagnosis and treatment.

AB - Precise monitoring of cancer treatment at the subcellular level remains a critical challenge. Therefore, a lysosome-specific AIE nanoprobe integrating stimulated emission depletion (STED) imaging and photodynamic therapy is reported here. The probe enables real-time visualization of lysosomal dynamics and reactive oxygen species (ROS)-mediated apoptosis, offering a powerful platform for high-resolution imaging-guided cancer diagnosis and treatment.

UR - https://www.scopus.com/pages/publications/105023849506

U2 - 10.1039/d5cc04640h

DO - 10.1039/d5cc04640h

M3 - 文章

C2 - 41347587

AN - SCOPUS:105023849506

SN - 1359-7345

VL - 62

SP - 568

EP - 571

JO - Chemical Communications

JF - Chemical Communications

IS - 2

ER -

Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process

Abstract

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