Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring

Yuchen Zeng; Anqi Wang; Wei Lv; Qingqing Wang; Shiqi Jiang; Xiaoguang Pan; Fei Wang; Huanming Yang; Lars Bolund; Chunhua Lin; Peng Han; Yonglun Luo

doi:10.1002/ctd2.183

Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring

Yuchen Zeng
, Anqi Wang
, Wei Lv
, Qingqing Wang
, Shiqi Jiang
, Xiaoguang Pan
, Fei Wang
, Huanming Yang
, Lars Bolund
, Chunhua Lin
, Peng Han
, Yonglun Luo

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

Urine-based liquid biopsy has emerged as a non-invasive and effective tool for early screening and diagnosis of bladder cancer. This review provides a comprehensive overview of the current urine-based biomarkers and methods for the detection and monitoring of bladder cancer. We focus on biomarkers including tumour DNAs, proteins, microbiome, tumour RNAs, long non-coding RNAs, transfer RNA-derived fragments, messenger RNAs, microRNAs, circular RNAs, exosomes and extrachromosomal circular DNA.

Original language	English
Article number	e183
Journal	Clinical and Translational Discovery
Volume	3
Issue number	2
DOIs	https://doi.org/10.1002/ctd2.183
State	Published - Apr 2023
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

biomarkers
bladder cancer
liquid biopsy
urine

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10.1002/ctd2.183

Cite this

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title = "Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring",

abstract = "Urine-based liquid biopsy has emerged as a non-invasive and effective tool for early screening and diagnosis of bladder cancer. This review provides a comprehensive overview of the current urine-based biomarkers and methods for the detection and monitoring of bladder cancer. We focus on biomarkers including tumour DNAs, proteins, microbiome, tumour RNAs, long non-coding RNAs, transfer RNA-derived fragments, messenger RNAs, microRNAs, circular RNAs, exosomes and extrachromosomal circular DNA.",

keywords = "biomarkers, bladder cancer, liquid biopsy, urine",

author = "Yuchen Zeng and Anqi Wang and Wei Lv and Qingqing Wang and Shiqi Jiang and Xiaoguang Pan and Fei Wang and Huanming Yang and Lars Bolund and Chunhua Lin and Peng Han and Yonglun Luo",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors. Clinical and Translational Discovery published by John Wiley \& Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.",

year = "2023",

month = apr,

doi = "10.1002/ctd2.183",

language = "英语",

volume = "3",

journal = "Clinical and Translational Discovery",

issn = "2768-0622",

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TY - JOUR

T1 - Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring

AU - Zeng, Yuchen

AU - Wang, Anqi

AU - Lv, Wei

AU - Wang, Qingqing

AU - Jiang, Shiqi

AU - Pan, Xiaoguang

AU - Wang, Fei

AU - Yang, Huanming

AU - Bolund, Lars

AU - Lin, Chunhua

AU - Han, Peng

AU - Luo, Yonglun

PY - 2023/4

Y1 - 2023/4

N2 - Urine-based liquid biopsy has emerged as a non-invasive and effective tool for early screening and diagnosis of bladder cancer. This review provides a comprehensive overview of the current urine-based biomarkers and methods for the detection and monitoring of bladder cancer. We focus on biomarkers including tumour DNAs, proteins, microbiome, tumour RNAs, long non-coding RNAs, transfer RNA-derived fragments, messenger RNAs, microRNAs, circular RNAs, exosomes and extrachromosomal circular DNA.

AB - Urine-based liquid biopsy has emerged as a non-invasive and effective tool for early screening and diagnosis of bladder cancer. This review provides a comprehensive overview of the current urine-based biomarkers and methods for the detection and monitoring of bladder cancer. We focus on biomarkers including tumour DNAs, proteins, microbiome, tumour RNAs, long non-coding RNAs, transfer RNA-derived fragments, messenger RNAs, microRNAs, circular RNAs, exosomes and extrachromosomal circular DNA.

KW - biomarkers

KW - bladder cancer

KW - liquid biopsy

KW - urine

UR - https://www.scopus.com/pages/publications/85165439160

U2 - 10.1002/ctd2.183

DO - 10.1002/ctd2.183

M3 - 文献综述

AN - SCOPUS:85165439160

SN - 2768-0622

VL - 3

JO - Clinical and Translational Discovery

JF - Clinical and Translational Discovery

IS - 2

M1 - e183

ER -

Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring

Abstract

UN SDGs

Keywords

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