Pyridinyl directed alkenylation with olefins via Rh(III)-catalyzed C-C bond cleavage of secondary arylmethanols

Hu Li; Yang Li; Xi Sha Zhang; Kang Chen; Xin Wang; Zhang Jie Shi

doi:10.1021/ja205228y

Pyridinyl directed alkenylation with olefins via Rh(III)-catalyzed C-C bond cleavage of secondary arylmethanols

Hu Li
, Yang Li
, Xi Sha Zhang
, Kang Chen
, Xin Wang
, Zhang Jie Shi

Research output: Contribution to journal › Article › peer-review

267 Scopus citations

Abstract

Novel C-C bond cleavage of secondary alcohols through Rh(III)-catalyzed β-carbon elimination directed by a pyridinyl group is reported. A five-membered rhodacycle is proposed as a key intermediate, which undergoes further alkenylation with various olefins. This novel transformation shows high efficiency along with excellent selectivity in mild conditions. A wide range of functionalities are compatible. This study offers a new strategy to carry out C-C bond activation.

Original language	English
Pages (from-to)	15244-15247
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	133
Issue number	39
DOIs	https://doi.org/10.1021/ja205228y
State	Published - 5 Oct 2011
Externally published	Yes

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title = "Pyridinyl directed alkenylation with olefins via Rh(III)-catalyzed C-C bond cleavage of secondary arylmethanols",

abstract = "Novel C-C bond cleavage of secondary alcohols through Rh(III)-catalyzed β-carbon elimination directed by a pyridinyl group is reported. A five-membered rhodacycle is proposed as a key intermediate, which undergoes further alkenylation with various olefins. This novel transformation shows high efficiency along with excellent selectivity in mild conditions. A wide range of functionalities are compatible. This study offers a new strategy to carry out C-C bond activation.",

author = "Hu Li and Yang Li and Zhang, \{Xi Sha\} and Kang Chen and Xin Wang and Shi, \{Zhang Jie\}",

year = "2011",

month = oct,

day = "5",

doi = "10.1021/ja205228y",

language = "英语",

volume = "133",

pages = "15244--15247",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

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T1 - Pyridinyl directed alkenylation with olefins via Rh(III)-catalyzed C-C bond cleavage of secondary arylmethanols

AU - Li, Hu

AU - Li, Yang

AU - Zhang, Xi Sha

AU - Chen, Kang

AU - Wang, Xin

AU - Shi, Zhang Jie

PY - 2011/10/5

Y1 - 2011/10/5

N2 - Novel C-C bond cleavage of secondary alcohols through Rh(III)-catalyzed β-carbon elimination directed by a pyridinyl group is reported. A five-membered rhodacycle is proposed as a key intermediate, which undergoes further alkenylation with various olefins. This novel transformation shows high efficiency along with excellent selectivity in mild conditions. A wide range of functionalities are compatible. This study offers a new strategy to carry out C-C bond activation.

AB - Novel C-C bond cleavage of secondary alcohols through Rh(III)-catalyzed β-carbon elimination directed by a pyridinyl group is reported. A five-membered rhodacycle is proposed as a key intermediate, which undergoes further alkenylation with various olefins. This novel transformation shows high efficiency along with excellent selectivity in mild conditions. A wide range of functionalities are compatible. This study offers a new strategy to carry out C-C bond activation.

UR - https://www.scopus.com/pages/publications/80053314804

U2 - 10.1021/ja205228y

DO - 10.1021/ja205228y

M3 - 文章

AN - SCOPUS:80053314804

SN - 0002-7863

VL - 133

SP - 15244

EP - 15247

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 39

ER -

Pyridinyl directed alkenylation with olefins via Rh(III)-catalyzed C-C bond cleavage of secondary arylmethanols

Abstract

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