Abstract
A pH-sensitive chitosan material was prepared via atom transfer radical polymerization (ATRP) of chitosan with poly (ethylene glycol) methacrylate (PEGMA), which was successfully conducted in water and methanol system with CS-Br as macroinitiator and CuBr/bpy as a catalyst. The copolymer obtained was analyzed. The results of UV analysis showed that at 24 °C and under different concentrations or at 24 °C and with pH value between 3.7-9, P (CS-Br-PEGMA) can well control delivery on coenzyme A, and the release mechanism of coenzyme A was also discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 49-51 |
| Number of pages | 3 |
| Journal | Xiandai Huagong/Modern Chemical Industry |
| Volume | 26 |
| Issue number | 10 |
| State | Published - Oct 2006 |
| Externally published | Yes |
Keywords
- Atom transfer radical polymerization (ATRP)
- Coenzyme A
- Controlled delivery
- PH-sensitivity
- Polymer P (CS-Br-PEGMA)
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