TY - GEN
T1 - Precisely controlled cavitation during the perfluorocarbon (PFC) nanodroplets assisted HIFU surgery
AU - Chang, Nan
AU - Wang, Xin
AU - Lu, Mingzhu
AU - Lu, Shukuan
AU - Wang, Supin
AU - Wan, Mingxi
N1 - Publisher Copyright:
© 2017 IEEE.
PY - 2017/10/31
Y1 - 2017/10/31
N2 - Previous study has demonstrated that pulsed HIFU with tens of microseconds pulse duration (PD) and 10kHz PRF is effective for cavitation generation. Meanwhile, with the assistance of PFC nanodroplets, cavitation can be further enhanced. Despite of higher efficiency, we also need cavitation to be precisely controlled and confined for sake of therapeutic safety, especially during the implementation of HIFU surgery in fine organs like brain, neuro, or blood vessel. Smaller focus is obtained by designing very large or spherical shaped transducers, which also cause some inconveniences for treatment. In our study, we propose a combinated ultrasound wave sequence to realize precisely controlled cavitation during PFC nanodroplets assisted HIFU to simultaneously achieve efficient and accurate therapy.
AB - Previous study has demonstrated that pulsed HIFU with tens of microseconds pulse duration (PD) and 10kHz PRF is effective for cavitation generation. Meanwhile, with the assistance of PFC nanodroplets, cavitation can be further enhanced. Despite of higher efficiency, we also need cavitation to be precisely controlled and confined for sake of therapeutic safety, especially during the implementation of HIFU surgery in fine organs like brain, neuro, or blood vessel. Smaller focus is obtained by designing very large or spherical shaped transducers, which also cause some inconveniences for treatment. In our study, we propose a combinated ultrasound wave sequence to realize precisely controlled cavitation during PFC nanodroplets assisted HIFU to simultaneously achieve efficient and accurate therapy.
UR - https://www.scopus.com/pages/publications/85039457915
U2 - 10.1109/ULTSYM.2017.8092787
DO - 10.1109/ULTSYM.2017.8092787
M3 - 会议稿件
AN - SCOPUS:85039457915
T3 - IEEE International Ultrasonics Symposium, IUS
BT - 2017 IEEE International Ultrasonics Symposium, IUS 2017
PB - IEEE Computer Society
T2 - 2017 IEEE International Ultrasonics Symposium, IUS 2017
Y2 - 6 September 2017 through 9 September 2017
ER -