TY - JOUR
T1 - Polymorphism profile of nine short tandem repeat Loci in the Han chinese.
AU - Li, Shuangding
AU - Yan, Chunxia
AU - Deng, Yajun
AU - Wang, Ruilin
AU - Wang, Jian
AU - Yang, Huanming
AU - Li, Shengbin
PY - 2003/5
Y1 - 2003/5
N2 - Nine short tandem repeat (STR) markers (D3S1358, VWA, FGA, THO1, TPOX, CSFIPO, D5S818, D13S317, and D7S820) and a sex-identification marker (Amelogenin locus) were amplified with multiplex PCR and were genotyped with a four-color fluorescence method in samples from 174 unrelated Han individuals in North China. The allele frequencies, genotype frequencies, heterozygosity, probability of discrimination powers, probability of paternity exclusion and Hardy-Weinberg equilibrium expectations were determined. The results demonstrated that the genotypes at all these STR loci in Han population conform to Hardy-Weinberg equilibrium expectations. The combined discrimination power (DP) was 1.05 x 10(-10) within nine STR loci analyzed and the probability of paternity exclusion (EPP) was 0.9998. The results indicate that these nine STR loci and the Amelogenin locus are useful markers for human identification, paternity and maternity testing and sex determination in forensic sciences.
AB - Nine short tandem repeat (STR) markers (D3S1358, VWA, FGA, THO1, TPOX, CSFIPO, D5S818, D13S317, and D7S820) and a sex-identification marker (Amelogenin locus) were amplified with multiplex PCR and were genotyped with a four-color fluorescence method in samples from 174 unrelated Han individuals in North China. The allele frequencies, genotype frequencies, heterozygosity, probability of discrimination powers, probability of paternity exclusion and Hardy-Weinberg equilibrium expectations were determined. The results demonstrated that the genotypes at all these STR loci in Han population conform to Hardy-Weinberg equilibrium expectations. The combined discrimination power (DP) was 1.05 x 10(-10) within nine STR loci analyzed and the probability of paternity exclusion (EPP) was 0.9998. The results indicate that these nine STR loci and the Amelogenin locus are useful markers for human identification, paternity and maternity testing and sex determination in forensic sciences.
UR - https://www.scopus.com/pages/publications/16644381819
U2 - 10.1016/S1672-0229(03)01020-9
DO - 10.1016/S1672-0229(03)01020-9
M3 - 文章
C2 - 15626346
AN - SCOPUS:16644381819
SN - 1672-0229
VL - 1
SP - 166
EP - 170
JO - Genomics, proteomics & bioinformatics / Beijing Genomics Institute
JF - Genomics, proteomics & bioinformatics / Beijing Genomics Institute
IS - 2
ER -