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Polymorphism of five X-STR loci in Chinese Achang ethnic group

  • Xi'an Jiaotong University

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: To investigate the genetic polymorphism and applied value in forensic medicine of five short tandem repeats (STRs) loci(DXS7130, DXS7132, DXS7133, DXS6804 and DXS8378) on X-chromosome in Achang ethnic group. METHODS: Allele frequency and genotype distribution of five X-STR loci among 100 unrelated individuals from Achang ethnic group were analyzed by PCR following polyacrylamide gel electrophoresis and silver staining. Hardy-Weinberg equilibrium of females was tested and forensic parameters were calculated. RESULT: All the five STR loci were polymorphic in Achang ethnic group. Chi-square test indicated that genotype distribution of females was in accordance with Hardy-Weinberg equilibrium. CONCLUSION: These results enrich Chinese genetic database and can be applied to individual identification, paternity testing and population genetics.

Original languageEnglish
Pages (from-to)185-190
Number of pages6
JournalZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
Volume36
Issue number2
StatePublished - Mar 2007

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