Physicochemical properties and structural evolution of synthetic substituted bioceramic in nano regime

Bo Wang; Kan Peng; Ke Xu; Peng Xu

doi:10.1016/j.matlet.2023.134455

Physicochemical properties and structural evolution of synthetic substituted bioceramic in nano regime

Bo Wang
, Kan Peng
, Ke Xu
, Peng Xu

Health Science Center

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

Abstract

Zinc-substituted fluorohydroxyapatite/beta-tricalcium phosphate (ZFHA/β-TCP) nanocrystals were prepared by a novel solid-state synthesis method. From Rietveld refinement of XRD patterns, no phase transformations and secondary phases were detected, and single-phase Zn²⁺-doped FA was observed as dopant concentration increased. A significant increase in crystallite sizes was observed after heat treatment at 900 °C. Spheroidal nanoparticles with an average particle size of 44.0 ± 6.4 nm and a narrow particle size distribution were detected by electron microscopy. 98% and 100% reductions in the number of colonies were observed for ZFHA/β-TCP against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli), respectively. A typical apatite layer was developed on the surface of the substituted structure even after 3 days of immersion in simulated body fluid (SBF).

Original language	English
Article number	134455
Journal	Materials Letters
Volume	345
DOIs	https://doi.org/10.1016/j.matlet.2023.134455
State	Published - 15 Aug 2023

Keywords

Bioceramics
Crystal structure
Electron microscopy
Nanoparticles
X-ray techniques

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10.1016/j.matlet.2023.134455

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title = "Physicochemical properties and structural evolution of synthetic substituted bioceramic in nano regime",

abstract = "Zinc-substituted fluorohydroxyapatite/beta-tricalcium phosphate (ZFHA/β-TCP) nanocrystals were prepared by a novel solid-state synthesis method. From Rietveld refinement of XRD patterns, no phase transformations and secondary phases were detected, and single-phase Zn2+-doped FA was observed as dopant concentration increased. A significant increase in crystallite sizes was observed after heat treatment at 900 °C. Spheroidal nanoparticles with an average particle size of 44.0 ± 6.4 nm and a narrow particle size distribution were detected by electron microscopy. 98\% and 100\% reductions in the number of colonies were observed for ZFHA/β-TCP against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli), respectively. A typical apatite layer was developed on the surface of the substituted structure even after 3 days of immersion in simulated body fluid (SBF).",

keywords = "Bioceramics, Crystal structure, Electron microscopy, Nanoparticles, X-ray techniques",

author = "Bo Wang and Kan Peng and Ke Xu and Peng Xu",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier B.V.",

year = "2023",

month = aug,

day = "15",

doi = "10.1016/j.matlet.2023.134455",

language = "英语",

volume = "345",

journal = "Materials Letters",

issn = "0167-577X",

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TY - JOUR

T1 - Physicochemical properties and structural evolution of synthetic substituted bioceramic in nano regime

AU - Wang, Bo

AU - Peng, Kan

AU - Xu, Ke

AU - Xu, Peng

PY - 2023/8/15

Y1 - 2023/8/15

N2 - Zinc-substituted fluorohydroxyapatite/beta-tricalcium phosphate (ZFHA/β-TCP) nanocrystals were prepared by a novel solid-state synthesis method. From Rietveld refinement of XRD patterns, no phase transformations and secondary phases were detected, and single-phase Zn2+-doped FA was observed as dopant concentration increased. A significant increase in crystallite sizes was observed after heat treatment at 900 °C. Spheroidal nanoparticles with an average particle size of 44.0 ± 6.4 nm and a narrow particle size distribution were detected by electron microscopy. 98% and 100% reductions in the number of colonies were observed for ZFHA/β-TCP against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli), respectively. A typical apatite layer was developed on the surface of the substituted structure even after 3 days of immersion in simulated body fluid (SBF).

AB - Zinc-substituted fluorohydroxyapatite/beta-tricalcium phosphate (ZFHA/β-TCP) nanocrystals were prepared by a novel solid-state synthesis method. From Rietveld refinement of XRD patterns, no phase transformations and secondary phases were detected, and single-phase Zn2+-doped FA was observed as dopant concentration increased. A significant increase in crystallite sizes was observed after heat treatment at 900 °C. Spheroidal nanoparticles with an average particle size of 44.0 ± 6.4 nm and a narrow particle size distribution were detected by electron microscopy. 98% and 100% reductions in the number of colonies were observed for ZFHA/β-TCP against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli), respectively. A typical apatite layer was developed on the surface of the substituted structure even after 3 days of immersion in simulated body fluid (SBF).

KW - Bioceramics

KW - Crystal structure

KW - Electron microscopy

KW - Nanoparticles

KW - X-ray techniques

UR - https://www.scopus.com/pages/publications/85158821610

U2 - 10.1016/j.matlet.2023.134455

DO - 10.1016/j.matlet.2023.134455

M3 - 文章

AN - SCOPUS:85158821610

SN - 0167-577X

VL - 345

JO - Materials Letters

JF - Materials Letters

M1 - 134455

ER -

Physicochemical properties and structural evolution of synthetic substituted bioceramic in nano regime

Abstract

Keywords

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