Perfusion computed tomography image reconstruction using spatio-temporal constrained edge-preserving prior

  • H. Zhang
  • , J. Ma
  • , J. Huang
  • , Z. Bian
  • , L. Tian
  • , L. Lu
  • , Y. Gao
  • , J. Li
  • , W. Chen

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Cerebral perfusion CT (PCT) imaging has been increasingly used in clinics, which can provide crucial cerebral perfusion parameters of a patient for checking acute stroke or other cerebrovascular diseases. Meanwhile, the associated Xray radiation in PCT imaging has arisen a significant concern in CT fields. In this paper, a spatio-temporal constrained (STC) edge-preserving prior was proposed for yielding high quality images in low-dose PCT reconstruction. Rather than taking each frame independently, we consider the time series PCT image as an entity. The present STC prior with the "time" dimensions is explicitly incorporated into the reconstruction process by using spatial and temporal constraints. A modified digital Shepp-Logan phantom and some clinical brain perfusion CT images were acquired to evaluate the present STC edge-preserving based iterative image reconstruction approach. The results show that the presented algorithm could yield images with suppressed the noise-induced artifacts. More important, the associated brain perfusion parameters can be calculated more reliable and accuracy than the commercial used FBP method.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering
Pages838-841
Number of pages4
DOIs
StatePublished - 2013
Externally publishedYes
EventWorld Congress on Medical Physics and Biomedical Engineering - Beijing, China
Duration: 26 May 201231 May 2012

Publication series

NameIFMBE Proceedings
Volume39 IFMBE
ISSN (Print)1680-0737

Conference

ConferenceWorld Congress on Medical Physics and Biomedical Engineering
Country/TerritoryChina
CityBeijing
Period26/05/1231/05/12

Keywords

  • Spatio-Temporal constrain
  • edge-preserving prior
  • low-dose
  • perfusion CT

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