Abstract
A matrix metalloproteinase-cleavable peptide-linked block copolymer was fabricated and utilized to construct PEG-sheddable polyplex micelles as smart gene delivery vectors, which were demonstrated to exhibit higher cellular uptake, improved endosomal escape, and high-efficiency gene transfection in the presence of matrix metalloproteinase-2.
| Original language | English |
|---|---|
| Pages (from-to) | 6974-6976 |
| Number of pages | 3 |
| Journal | Chemical Communications |
| Volume | 49 |
| Issue number | 62 |
| DOIs | |
| State | Published - 9 Jul 2013 |
| Externally published | Yes |