Palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters to form five-membered nitrogenated heterocyclic conjugated trienes

Ting He; Pin Gao; Shan Fang; Yaling Chi; Yuantao Chen

doi:10.1016/j.tetlet.2017.11.018

Palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters to form five-membered nitrogenated heterocyclic conjugated trienes

Ting He
, Pin Gao
, Shan Fang
, Yaling Chi
, Yuantao Chen

School of Chemistry

Qinghai Normal University

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters have been developed. This cyclization reaction shows excellent regioselectivity and good functional group tolerance to obtain five-membered nitrogenated heterocyclic conjugated trienes in moderate to excellent yields. The resulting conjugated trienes could be facilely converted to highly substituted benzenes through Diels-Alder reactions.

Original language	English
Pages (from-to)	4832-4835
Number of pages	4
Journal	Tetrahedron Letters
Volume	58
Issue number	52
DOIs	https://doi.org/10.1016/j.tetlet.2017.11.018
State	Published - 27 Dec 2017

Keywords

1,6-Enynes
Conjugated trienes
Cycloisomerisation
Nitrogenated heterocyclic
Palladium-catalyzed

Access to Document

10.1016/j.tetlet.2017.11.018

Cite this

@article{d3367277765e4f04841410b99539f8b8,

title = "Palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters to form five-membered nitrogenated heterocyclic conjugated trienes",

abstract = "A palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters have been developed. This cyclization reaction shows excellent regioselectivity and good functional group tolerance to obtain five-membered nitrogenated heterocyclic conjugated trienes in moderate to excellent yields. The resulting conjugated trienes could be facilely converted to highly substituted benzenes through Diels-Alder reactions.",

keywords = "1,6-Enynes, Conjugated trienes, Cycloisomerisation, Nitrogenated heterocyclic, Palladium-catalyzed",

author = "Ting He and Pin Gao and Shan Fang and Yaling Chi and Yuantao Chen",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Ltd",

year = "2017",

month = dec,

day = "27",

doi = "10.1016/j.tetlet.2017.11.018",

language = "英语",

volume = "58",

pages = "4832--4835",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "52",

}

TY - JOUR

T1 - Palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters to form five-membered nitrogenated heterocyclic conjugated trienes

AU - He, Ting

AU - Gao, Pin

AU - Fang, Shan

AU - Chi, Yaling

AU - Chen, Yuantao

PY - 2017/12/27

Y1 - 2017/12/27

N2 - A palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters have been developed. This cyclization reaction shows excellent regioselectivity and good functional group tolerance to obtain five-membered nitrogenated heterocyclic conjugated trienes in moderate to excellent yields. The resulting conjugated trienes could be facilely converted to highly substituted benzenes through Diels-Alder reactions.

AB - A palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters have been developed. This cyclization reaction shows excellent regioselectivity and good functional group tolerance to obtain five-membered nitrogenated heterocyclic conjugated trienes in moderate to excellent yields. The resulting conjugated trienes could be facilely converted to highly substituted benzenes through Diels-Alder reactions.

KW - 1,6-Enynes

KW - Conjugated trienes

KW - Cycloisomerisation

KW - Nitrogenated heterocyclic

KW - Palladium-catalyzed

UR - https://www.scopus.com/pages/publications/85035102950

U2 - 10.1016/j.tetlet.2017.11.018

DO - 10.1016/j.tetlet.2017.11.018

M3 - 文章

AN - SCOPUS:85035102950

SN - 0040-4039

VL - 58

SP - 4832

EP - 4835

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 52

ER -

Palladium-catalyzed cycloisomerisation reaction of 1,6-enyne acetic esters to form five-membered nitrogenated heterocyclic conjugated trienes

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this