Abstract
OBJECTIVE: To evaluate the efficacy and safety of the oral combination chemotherapy of furtulon (FTL) and cyclophosphamide (CTX) for advanced breast cancer (ABC). METHODS: From Jun 2000 to Jun 2002, eighty-three patients with ABC were treated with the two oral drugs as combined chemotherapy. The mean number of cycles was 5, median number of cycles was 6 (range 2-6). RESULTS: The overall response rate was 45.8%, The median time to progression was 6 months. The treatment was well tolerated, with related Grade 3 clinical adverse effect being only nausea and vomiting in 2 patients (2.4%) and mild hematologic toxicities. CONCLUSION: Oral combined chemotherapy of FTL and CTX, being convenient and safe, is effective for patients with advanced breast cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 282-284 |
| Number of pages | 3 |
| Journal | Zhonghua zhong liu za zhi [Chinese journal of oncology] |
| Volume | 25 |
| Issue number | 3 |
| State | Published - May 2003 |
