TY - GEN
T1 - Optimizing electrochemical-impedance-spectroscopy-based immunoassays on zinc-oxide-nanowire paper-based electrodes
AU - Li, Xiao
AU - Fu, Hao
AU - Li, Ted
AU - Liu, Xinyu
N1 - Publisher Copyright:
© 2019 CBMS-0001.
PY - 2019
Y1 - 2019
N2 - Infectious diseases cause tremendous morbidity/mortality and economic burdens to developing countries. Accurate, affordable and rapid diagnostic tools play a significant role in mitigating the public health challenges. Among a variety of point-of-care diagnostic tools, microfluidic paper-based analytical devices (µPADs) stand out as a particularly promising technology [1]. We have developed a µPAD integrating zinc oxide nanowires (ZnO NWs), and applied it to enzymatic glucose sensing [2] and electrochemical impedance spectrometry (EIS)-based immunoassays [3]. The EIS-based immunoassay is label-free, rapid (25 min), and highly sensitive. Here, we report the experimental optimization of design parameters of the ZnO-NW µPAD for EIS-based immunoassay.
AB - Infectious diseases cause tremendous morbidity/mortality and economic burdens to developing countries. Accurate, affordable and rapid diagnostic tools play a significant role in mitigating the public health challenges. Among a variety of point-of-care diagnostic tools, microfluidic paper-based analytical devices (µPADs) stand out as a particularly promising technology [1]. We have developed a µPAD integrating zinc oxide nanowires (ZnO NWs), and applied it to enzymatic glucose sensing [2] and electrochemical impedance spectrometry (EIS)-based immunoassays [3]. The EIS-based immunoassay is label-free, rapid (25 min), and highly sensitive. Here, we report the experimental optimization of design parameters of the ZnO-NW µPAD for EIS-based immunoassay.
KW - Electrochemical impedance spectroscopy
KW - Paper-based biosensor
KW - Zinc oxide nanowire
UR - https://www.scopus.com/pages/publications/85094974004
M3 - 会议稿件
AN - SCOPUS:85094974004
T3 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
SP - 667
EP - 668
BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PB - Chemical and Biological Microsystems Society
T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Y2 - 27 October 2019 through 31 October 2019
ER -
