TY - GEN
T1 - On-site monitoring of steroid hormones in environmental waters with a low-cost, integrated polymer lab-on-chip device
AU - Matos Pires, Nuno Miguel
AU - Dong, Tao
PY - 2014
Y1 - 2014
N2 - Routine analysis of steroid hormones in environmental water samples demands for cost-effective tools that can detect multiple targets simultaneously. This study reports a high-throughput polymer platform integrated to polymer optical sensors for on-site monitoring of hormones in water. This opto-microfluidic device concept is fully compatible to low-cost fabrication methods. A competitive chemiluminescence immunoassay was performed onto gold thin film coated chambers, and a detection resolution of roughly 0.2 ng/mL was obtained using 17β-estradiol as the model target. Furthermore, the integrated polymer platform showed good recovery for the estradiol target when spiked in surface water samples.
AB - Routine analysis of steroid hormones in environmental water samples demands for cost-effective tools that can detect multiple targets simultaneously. This study reports a high-throughput polymer platform integrated to polymer optical sensors for on-site monitoring of hormones in water. This opto-microfluidic device concept is fully compatible to low-cost fabrication methods. A competitive chemiluminescence immunoassay was performed onto gold thin film coated chambers, and a detection resolution of roughly 0.2 ng/mL was obtained using 17β-estradiol as the model target. Furthermore, the integrated polymer platform showed good recovery for the estradiol target when spiked in surface water samples.
KW - Environmental monitoring
KW - Hormone detection
KW - Polymer lab-on-a-chip
KW - Water analysis
UR - https://www.scopus.com/pages/publications/84887539582
U2 - 10.4028/www.scientific.net/AMM.448-453.396
DO - 10.4028/www.scientific.net/AMM.448-453.396
M3 - 会议稿件
AN - SCOPUS:84887539582
SN - 9783037859124
T3 - Applied Mechanics and Materials
SP - 396
EP - 401
BT - Renewable Energy and Environmental Technology
T2 - 2013 International Conference on Renewable Energy and Environmental Technology, REET 2013
Y2 - 21 September 2013 through 22 September 2013
ER -