Nickel-Catalyzed Stereoselective Diarylation of Alkenylarenes

  • Pin Gao
  • , Liang An Chen
  • , M. Kevin Brown

Research output: Contribution to journalArticlepeer-review

129 Scopus citations

Abstract

A three-component coupling of aryl bromides, arylboron reagents, and alkenylarenes is presented. The method tolerates a variety of substitution patterns on all of the components. In particular, 1,2-disubstituted alkenylarenes are suitable and undergo highly diastereoselective diarylation.

Original languageEnglish
Pages (from-to)10653-10657
Number of pages5
JournalJournal of the American Chemical Society
Volume140
Issue number34
DOIs
StatePublished - 29 Aug 2018

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