MSY2: A slowly evolving minisatellite on the human Y chromosome which provides a useful polymorphic marker in Chinese populations

Weidong Bao; Suling Zhu; Arpita Pandya; Tatiana Zerjal; Jiujin Xu; Qunfang Shu; Ruofu Du; Huanming Yang; Chris Tyler-Smith

doi:10.1016/S0378-1119(00)00021-4

MSY2: A slowly evolving minisatellite on the human Y chromosome which provides a useful polymorphic marker in Chinese populations

Weidong Bao
, Suling Zhu
, Arpita Pandya
, Tatiana Zerjal
, Jiujin Xu
, Qunfang Shu
, Ruofu Du
, Huanming Yang
, Chris Tyler-Smith

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

We present the second human Y-specific minisatellite, MSY2 (DYS440). It consists of three or four copies of a 99-110 bp repeat unit and is located about 1 kb upstream of the DBY gene. The most common allele contains four units, but a three-unit allele has arisen on at least four occasions; in chimpanzees and orangutans, MSY2 contains only two units. It is therefore evolving slowly and provides a particularly useful polymorphic marker for Chinese populations. (C) 2000 Elsevier Science B.V.

Original language	English
Pages (from-to)	29-33
Number of pages	5
Journal	Gene
Volume	244
Issue number	1-2
DOIs	https://doi.org/10.1016/S0378-1119(00)00021-4
State	Published - 22 Feb 2000
Externally published	Yes

Keywords

Ape
DNA polymorphism
Human diversity
Human evolution
Male lineage

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10.1016/S0378-1119(00)00021-4

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title = "MSY2: A slowly evolving minisatellite on the human Y chromosome which provides a useful polymorphic marker in Chinese populations",

abstract = "We present the second human Y-specific minisatellite, MSY2 (DYS440). It consists of three or four copies of a 99-110 bp repeat unit and is located about 1 kb upstream of the DBY gene. The most common allele contains four units, but a three-unit allele has arisen on at least four occasions; in chimpanzees and orangutans, MSY2 contains only two units. It is therefore evolving slowly and provides a particularly useful polymorphic marker for Chinese populations. (C) 2000 Elsevier Science B.V.",

keywords = "Ape, DNA polymorphism, Human diversity, Human evolution, Male lineage",

author = "Weidong Bao and Suling Zhu and Arpita Pandya and Tatiana Zerjal and Jiujin Xu and Qunfang Shu and Ruofu Du and Huanming Yang and Chris Tyler-Smith",

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doi = "10.1016/S0378-1119(00)00021-4",

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T2 - A slowly evolving minisatellite on the human Y chromosome which provides a useful polymorphic marker in Chinese populations

AU - Bao, Weidong

AU - Zhu, Suling

AU - Pandya, Arpita

AU - Zerjal, Tatiana

AU - Xu, Jiujin

AU - Shu, Qunfang

AU - Du, Ruofu

AU - Yang, Huanming

AU - Tyler-Smith, Chris

PY - 2000/2/22

Y1 - 2000/2/22

N2 - We present the second human Y-specific minisatellite, MSY2 (DYS440). It consists of three or four copies of a 99-110 bp repeat unit and is located about 1 kb upstream of the DBY gene. The most common allele contains four units, but a three-unit allele has arisen on at least four occasions; in chimpanzees and orangutans, MSY2 contains only two units. It is therefore evolving slowly and provides a particularly useful polymorphic marker for Chinese populations. (C) 2000 Elsevier Science B.V.

AB - We present the second human Y-specific minisatellite, MSY2 (DYS440). It consists of three or four copies of a 99-110 bp repeat unit and is located about 1 kb upstream of the DBY gene. The most common allele contains four units, but a three-unit allele has arisen on at least four occasions; in chimpanzees and orangutans, MSY2 contains only two units. It is therefore evolving slowly and provides a particularly useful polymorphic marker for Chinese populations. (C) 2000 Elsevier Science B.V.

KW - Ape

KW - DNA polymorphism

KW - Human diversity

KW - Human evolution

KW - Male lineage

UR - https://www.scopus.com/pages/publications/0033952762

U2 - 10.1016/S0378-1119(00)00021-4

DO - 10.1016/S0378-1119(00)00021-4

M3 - 文章

C2 - 10689184

AN - SCOPUS:0033952762

SN - 0378-1119

VL - 244

SP - 29

EP - 33

JO - Gene

JF - Gene

IS - 1-2

ER -

MSY2: A slowly evolving minisatellite on the human Y chromosome which provides a useful polymorphic marker in Chinese populations

Abstract

Keywords

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