Abstract
Microfluidics brings unique opportunities for the synthesis of nanomaterials toward efficient liquid biopsy. Herein, we developed the microreactor-enabled flow synthesis of immunomagnetic nanomaterials with controllable shapes (sphere, cube, rod, and belt) by simply tuning the flow rates. The particle shape-dependent screening efficiency of circulating tumor cells was first investigated and compared with commercial ferrofluids, providing new insights into the rational design of a particulate system toward the screening and analysis of circulating tumor biomarkers.
| Original language | English |
|---|---|
| Pages (from-to) | 1997-2002 |
| Number of pages | 6 |
| Journal | Lab on a Chip |
| Volume | 18 |
| Issue number | 14 |
| DOIs | |
| State | Published - 21 Jul 2018 |
| Externally published | Yes |