Microfluidic synthesis of multifunctional hollow mesoporous silica nanospheres

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Hollow mesoporous silica spheres with an average diameter of ~800 nm and a shell layer of ~20 nm are synthesized in mixing-enhanced microfluidic spiral channels. The hollow structure and uniform size distribution of the spheres are obtained by consideration towards channel geometry design and by tuning the concentrations and flow rates of two reagents: cetyltrimethylammonium bromide and tetraethylorthosilicate. With the same microfluidic platform, multifunctional silica nanospheres integrated with proteins, quantum dots and magnetic nanoparticles can be further synthesized. These hollow and multifunctional nanospheres have great applications in biomedical engineering such as dye adsorption, drug delivery and cell imaging.

Original languageEnglish
Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PublisherChemical and Biological Microsystems Society
Pages366-368
Number of pages3
ISBN (Electronic)9780692941836
StatePublished - 2020
Externally publishedYes
Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
Duration: 22 Oct 201726 Oct 2017

Publication series

Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
Country/TerritoryUnited States
CitySavannah
Period22/10/1726/10/17

Keywords

  • Hollow
  • Microfluidics
  • Multifunctional
  • Nanospheres

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