Metal-free oxidative hydroxyalkylarylation of activated alkenes by direct sp3 C–H functionalization of alcohols

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Abstract

A metal-free tandem radical addition/cyclization reaction of activated alkenes and alcohols has been developed. The process provides an efficient and atom economical access to various valuable hydroxyl-containing oxindoles through the direct sp3 C–H functionalization of alcohols.

Original languageEnglish
Pages (from-to)7540-7542
Number of pages3
JournalChemical Communications
Volume49
Issue number68
DOIs
StatePublished - 30 Jul 2013

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