Mechanomedicine targeting brown adipose tissue for metabolic health

Hui Yang; Shanshan Zhu; Zhe Yang; Bin Gao; Shaoyong Xu; Feng Xu

doi:10.1016/j.tem.2025.07.007

Mechanomedicine targeting brown adipose tissue for metabolic health

Hui Yang
, Shanshan Zhu
, Zhe Yang
, Bin Gao
, Shaoyong Xu
, Feng Xu

School of Life Science and Technology (SLST)

Hubei University of Arts and Science
Xi'an Jiaotong University
Hainan Medical University
Tangdu Hospital, Fourth Military Medical University

Research output: Contribution to journal › Short survey › peer-review

Abstract

Brown adipose tissue (BAT) is a compelling therapeutic target against metabolic diseases. Mechanical cues regulate BAT function and may offer novel, non-pharmacological therapeutic approaches. Herein, we discuss the biomechanical pathways underlying BAT activation, highlight advances in mechanotherapeutic strategies, and consider how emerging technologies may enhance these interventions.

Original language	English
Pages (from-to)	874-877
Number of pages	4
Journal	Trends in Endocrinology and Metabolism
Volume	36
Issue number	10
DOIs	https://doi.org/10.1016/j.tem.2025.07.007
State	Published - Oct 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.tem.2025.07.007

Cite this

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title = "Mechanomedicine targeting brown adipose tissue for metabolic health",

abstract = "Brown adipose tissue (BAT) is a compelling therapeutic target against metabolic diseases. Mechanical cues regulate BAT function and may offer novel, non-pharmacological therapeutic approaches. Herein, we discuss the biomechanical pathways underlying BAT activation, highlight advances in mechanotherapeutic strategies, and consider how emerging technologies may enhance these interventions.",

author = "Hui Yang and Shanshan Zhu and Zhe Yang and Bin Gao and Shaoyong Xu and Feng Xu",

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T1 - Mechanomedicine targeting brown adipose tissue for metabolic health

AU - Yang, Hui

AU - Zhu, Shanshan

AU - Yang, Zhe

AU - Gao, Bin

AU - Xu, Shaoyong

AU - Xu, Feng

PY - 2025/10

Y1 - 2025/10

N2 - Brown adipose tissue (BAT) is a compelling therapeutic target against metabolic diseases. Mechanical cues regulate BAT function and may offer novel, non-pharmacological therapeutic approaches. Herein, we discuss the biomechanical pathways underlying BAT activation, highlight advances in mechanotherapeutic strategies, and consider how emerging technologies may enhance these interventions.

AB - Brown adipose tissue (BAT) is a compelling therapeutic target against metabolic diseases. Mechanical cues regulate BAT function and may offer novel, non-pharmacological therapeutic approaches. Herein, we discuss the biomechanical pathways underlying BAT activation, highlight advances in mechanotherapeutic strategies, and consider how emerging technologies may enhance these interventions.

UR - https://www.scopus.com/pages/publications/105013141310

U2 - 10.1016/j.tem.2025.07.007

DO - 10.1016/j.tem.2025.07.007

M3 - 短篇评述

C2 - 40813182

AN - SCOPUS:105013141310

SN - 1043-2760

VL - 36

SP - 874

EP - 877

JO - Trends in Endocrinology and Metabolism

JF - Trends in Endocrinology and Metabolism

IS - 10

ER -

Mechanomedicine targeting brown adipose tissue for metabolic health

Abstract

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