Iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds relying on alkoxyl radical induced cascade

Pin Gao; Hao Wu; Jun Cheng Yang; Li Na Guo

doi:10.1021/acs.orglett.9b02675

Iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds relying on alkoxyl radical induced cascade

Pin Gao
, Hao Wu
, Jun Cheng Yang
, Li Na Guo

School of Chemistry

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

An iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds via alkoxyl radical induced C-C bond cleavage is presented. This protocol features mild conditions (room temperature, redox-neutral), good substrate scope and functional group compatibility, as well as excellent stereoselectivity, thus providing a facile access to the distal alkenyl ketones.

Original language	English
Pages (from-to)	7104-7108
Number of pages	5
Journal	Organic Letters
Volume	21
Issue number	17
DOIs	https://doi.org/10.1021/acs.orglett.9b02675
State	Published - 6 Sep 2019

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title = "Iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds relying on alkoxyl radical induced cascade",

abstract = "An iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds via alkoxyl radical induced C-C bond cleavage is presented. This protocol features mild conditions (room temperature, redox-neutral), good substrate scope and functional group compatibility, as well as excellent stereoselectivity, thus providing a facile access to the distal alkenyl ketones.",

author = "Pin Gao and Hao Wu and Yang, \{Jun Cheng\} and Guo, \{Li Na\}",

note = "Publisher Copyright: {\textcopyright} 2019 American Chemical Society.",

year = "2019",

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doi = "10.1021/acs.orglett.9b02675",

language = "英语",

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journal = "Organic Letters",

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T1 - Iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds relying on alkoxyl radical induced cascade

AU - Gao, Pin

AU - Wu, Hao

AU - Yang, Jun Cheng

AU - Guo, Li Na

PY - 2019/9/6

Y1 - 2019/9/6

N2 - An iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds via alkoxyl radical induced C-C bond cleavage is presented. This protocol features mild conditions (room temperature, redox-neutral), good substrate scope and functional group compatibility, as well as excellent stereoselectivity, thus providing a facile access to the distal alkenyl ketones.

AB - An iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds via alkoxyl radical induced C-C bond cleavage is presented. This protocol features mild conditions (room temperature, redox-neutral), good substrate scope and functional group compatibility, as well as excellent stereoselectivity, thus providing a facile access to the distal alkenyl ketones.

UR - https://www.scopus.com/pages/publications/85072330187

U2 - 10.1021/acs.orglett.9b02675

DO - 10.1021/acs.orglett.9b02675

M3 - 文章

C2 - 31448922

AN - SCOPUS:85072330187

SN - 1523-7060

VL - 21

SP - 7104

EP - 7108

JO - Organic Letters

JF - Organic Letters

IS - 17

ER -

Iron-catalyzed decarboxylative olefination of unstrained carbon-carbon bonds relying on alkoxyl radical induced cascade

Abstract

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