Iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation: a new approach to functionalized S-alkyl phosphorothioates

Ming Bai; Shuai Liu; Hong Xin; Xu Yang; Xin Hua Duan; Li Na Guo

doi:10.1039/d3ob00673e

Iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation: a new approach to functionalized S-alkyl phosphorothioates

Ming Bai
, Shuai Liu
, Hong Xin
, Xu Yang
, Xin Hua Duan
, Li Na Guo

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

An efficient iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation cascade is presented. This protocol features mild and redox neutral conditions, wide substrate scope and easy scalability, allowing straightforward access to functionalized S-alkyl organophosphorus compounds in moderate to good yields.

Original language	English
Pages (from-to)	5855-5860
Number of pages	6
Journal	Organic and Biomolecular Chemistry
Volume	21
Issue number	28
DOIs	https://doi.org/10.1039/d3ob00673e
State	Published - 28 Jun 2023

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10.1039/d3ob00673e

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title = "Iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation: a new approach to functionalized S-alkyl phosphorothioates",

abstract = "An efficient iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation cascade is presented. This protocol features mild and redox neutral conditions, wide substrate scope and easy scalability, allowing straightforward access to functionalized S-alkyl organophosphorus compounds in moderate to good yields.",

author = "Ming Bai and Shuai Liu and Hong Xin and Xu Yang and Duan, \{Xin Hua\} and Guo, \{Li Na\}",

note = "Publisher Copyright: {\textcopyright} 2023 The Royal Society of Chemistry.",

year = "2023",

month = jun,

day = "28",

doi = "10.1039/d3ob00673e",

language = "英语",

volume = "21",

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journal = "Organic and Biomolecular Chemistry",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation

T2 - a new approach to functionalized S-alkyl phosphorothioates

AU - Bai, Ming

AU - Liu, Shuai

AU - Xin, Hong

AU - Yang, Xu

AU - Duan, Xin Hua

AU - Guo, Li Na

PY - 2023/6/28

Y1 - 2023/6/28

N2 - An efficient iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation cascade is presented. This protocol features mild and redox neutral conditions, wide substrate scope and easy scalability, allowing straightforward access to functionalized S-alkyl organophosphorus compounds in moderate to good yields.

AB - An efficient iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation cascade is presented. This protocol features mild and redox neutral conditions, wide substrate scope and easy scalability, allowing straightforward access to functionalized S-alkyl organophosphorus compounds in moderate to good yields.

UR - https://www.scopus.com/pages/publications/85165280421

U2 - 10.1039/d3ob00673e

DO - 10.1039/d3ob00673e

M3 - 文章

C2 - 37401815

AN - SCOPUS:85165280421

SN - 1477-0520

VL - 21

SP - 5855

EP - 5860

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 28

ER -

Iron-catalyzed alkoxyl radical-mediated C-C bond cleavage/phosphorothiolation: a new approach to functionalized S-alkyl phosphorothioates

Abstract

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