Influence of remote oxygen plasma sterilization on surface property of substrate material

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Abstract

Under the given conditions of remote oxygen plasma sterilization, the physical, chemical and medical properties of sterilized poly(tetrafluoroethylene) (PTFE) surface are investigated by water contact angle measurement, mass loss calculation, microorganism incubation and blood coagulation measuration in vitro, respectively. The surface analysis is characterized by X-ray photoelectron spectroscopy. The results show that remote oxygen plasma sterilization can induce polar oxygen functionalities onto the PTFE film surface to replace the F element, making the surface hydrophilicity enhanced within the distance of 0-40 cm from the center of plasma discharge. With the distance increasing, the surface damage of PTFE is restrained. The surface biocompatibility of remote oxygen plasma-sterilized PTFE film is also strengthened to a great extent, and the optimal effect can be obtained at the distance of 40 cm. Surface hydrophilicity is the pivotal factor for influencing the biocompatibility, while surface etching has no special relationship with it. Only when the optimal equilibrium is obtained between surface hydrophilicity and etching could the biocompatibility achieve the maximum improvement.

Original languageEnglish
Pages (from-to)82-86+115
JournalHsi-An Chiao Tung Ta Hsueh/Journal of Xi'an Jiaotong University
Volume43
Issue number3
StatePublished - Mar 2009

Keywords

  • Poly(tetrafluoroethylene)
  • Remote oxygen plasma
  • Sterilization
  • Surface property

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