In vivo quantitative reconstruction studies of bioluminescence tomography: Effects of peak-wavelength shift and model deviation

Bioluminescence tomography is a novel optical molecular imaging technology. The corresponding system, theory, and algorithmic frames have been set up. In the present study, we concentrated on the analysis of quantitative reconstruction deviation frompeak-wavelength shift of luminescent source and the deviation of heterogeneousmouse model. The findings suggest that the reconstruction results are significantly affected by the peak-wavelength shift and deviation of anatomical structure animal models. Furthermore, the model deviations exhibit much more influence than the wavelength shift on the reconstruction results.