TY - JOUR
T1 - Hypertrophic Lichenoid Eruption in a Child Successfully Treated Using Acitretin and Surgery
T2 - A Case Report and Literature Review
AU - Geng, Songmei
AU - Liu, Yanting
AU - Wang, Hao
AU - Yan, Huling
AU - Niu, Xinwu
AU - Toyohara, Jennifer P.
AU - Xiao, Shengxiang
N1 - Publisher Copyright:
© 2015 Wiley Periodicals, Inc.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - A 9-year-old boy presented with a history of keratotic violaceous plaques on the limbs and face for 8 years that had gradually progressed to erosive nodules on the extremities for 2 years. Several biopsies revealed hyperkeratosis, liquefactive degeneration of the basal layer, and a bandlike predominantly lymphocytic infiltrate. Based on the clinical and histologic findings, the patient was diagnosed with keratosis lichenoides chronica, a rare chronic dermatosis that is particularly uncommon in childhood. There are fewer than 20 reported cases of pediatric-onset keratosis lichenoides chronica in the current literature, with occurrence of pseudoepitheliomatous hyperplasia of primary keratosis lichenoides chronica lesions being even rarer. Here we present a unique pediatric-onset case accompanied by pseudoepitheliomatous hyperplasia that posed a significant treatment challenge to dermatologists. Significant improvement in the pseudoepitheliomatous skin lesions was achieved after treatment with oral acitretin capsules and surgical excision with skin grafting.
AB - A 9-year-old boy presented with a history of keratotic violaceous plaques on the limbs and face for 8 years that had gradually progressed to erosive nodules on the extremities for 2 years. Several biopsies revealed hyperkeratosis, liquefactive degeneration of the basal layer, and a bandlike predominantly lymphocytic infiltrate. Based on the clinical and histologic findings, the patient was diagnosed with keratosis lichenoides chronica, a rare chronic dermatosis that is particularly uncommon in childhood. There are fewer than 20 reported cases of pediatric-onset keratosis lichenoides chronica in the current literature, with occurrence of pseudoepitheliomatous hyperplasia of primary keratosis lichenoides chronica lesions being even rarer. Here we present a unique pediatric-onset case accompanied by pseudoepitheliomatous hyperplasia that posed a significant treatment challenge to dermatologists. Significant improvement in the pseudoepitheliomatous skin lesions was achieved after treatment with oral acitretin capsules and surgical excision with skin grafting.
UR - https://www.scopus.com/pages/publications/84948717133
U2 - 10.1111/pde.12658
DO - 10.1111/pde.12658
M3 - 文献综述
C2 - 26227743
AN - SCOPUS:84948717133
SN - 0736-8046
VL - 32
SP - e238-e241
JO - Pediatric Dermatology
JF - Pediatric Dermatology
IS - 6
ER -