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Histotripsy produced by dual frequency of fundamental and harmonic superimposition with protocol of hundred-microsecond-length pulses and two stages

  • Mingzhu Lu
  • , Rui Wang
  • , Yujiao Li
  • , Linglu Zhang
  • , Dan Han
  • , Yanshan Liu
  • , Mingxi Wan
  • Xi'an Jiaotong University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Histotripsy is a new non-invasive therapy modality and can mechanically disintegrating target tissue for tumor treatment. In this study, we propose a strategy of dual frequency of fundamental and harmonic superimposition combined with hundred-microsecond-length pulses and two stages to get good use of the nonlinear regimes of enhanced cavitation and boiling. Confocal fundamental and harmonic superimposition can greatly lower the cavitation threshold and enhance cavitation activity via wave interference.

Original languageEnglish
Title of host publication2017 IEEE International Ultrasonics Symposium, IUS 2017
PublisherIEEE Computer Society
ISBN (Electronic)9781538633830
DOIs
StatePublished - 31 Oct 2017
Event2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, United States
Duration: 6 Sep 2017 → 9 Sep 2017

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2017 IEEE International Ultrasonics Symposium, IUS 2017
Country/TerritoryUnited States
CityWashington
Period6/09/17 → 9/09/17

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