Highly regioselective synthesis of spirocyclic compounds by a palladium-catalyzed intermolecular tandem reaction

Hai Peng Bi; Xue Yuan Liu; Fa Rong Gou; Li Na Guo; Xin Hua Duan; Xing Zhong Shu; Yong Min Liang

doi:10.1002/anie.200702238

Highly regioselective synthesis of spirocyclic compounds by a palladium-catalyzed intermolecular tandem reaction

Hai Peng Bi
, Xue Yuan Liu
, Fa Rong Gou
, Li Na Guo
, Xin Hua Duan
, Xing Zhong Shu
, Yong Min Liang

School of Chemistry

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

(Chemical Equation Presented) Bicycles built for two: The palladium-catalyzed intermolecular tandem reaction of propargylic compounds with 2-iodophenols offers an efficient, direct route to spirocyclic compounds with high regioselectivity. The reaction conditions and the scope of the process are examined, and a possible mechanism is proposed.

Original language	English
Pages (from-to)	7068-7071
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	37
DOIs	https://doi.org/10.1002/anie.200702238
State	Published - 2007

Keywords

Cyclization
Palladium
Spiro compounds
Tandem reactions

Access to Document

10.1002/anie.200702238

Cite this

@article{47eb307f20624948b20e18492c57db86,

title = "Highly regioselective synthesis of spirocyclic compounds by a palladium-catalyzed intermolecular tandem reaction",

abstract = "(Chemical Equation Presented) Bicycles built for two: The palladium-catalyzed intermolecular tandem reaction of propargylic compounds with 2-iodophenols offers an efficient, direct route to spirocyclic compounds with high regioselectivity. The reaction conditions and the scope of the process are examined, and a possible mechanism is proposed.",

keywords = "Cyclization, Palladium, Spiro compounds, Tandem reactions",

author = "Bi, \{Hai Peng\} and Liu, \{Xue Yuan\} and Gou, \{Fa Rong\} and Guo, \{Li Na\} and Duan, \{Xin Hua\} and Shu, \{Xing Zhong\} and Liang, \{Yong Min\}",

year = "2007",

doi = "10.1002/anie.200702238",

language = "英语",

volume = "46",

pages = "7068--7071",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "37",

}

TY - JOUR

T1 - Highly regioselective synthesis of spirocyclic compounds by a palladium-catalyzed intermolecular tandem reaction

AU - Bi, Hai Peng

AU - Liu, Xue Yuan

AU - Gou, Fa Rong

AU - Guo, Li Na

AU - Duan, Xin Hua

AU - Shu, Xing Zhong

AU - Liang, Yong Min

PY - 2007

Y1 - 2007

N2 - (Chemical Equation Presented) Bicycles built for two: The palladium-catalyzed intermolecular tandem reaction of propargylic compounds with 2-iodophenols offers an efficient, direct route to spirocyclic compounds with high regioselectivity. The reaction conditions and the scope of the process are examined, and a possible mechanism is proposed.

AB - (Chemical Equation Presented) Bicycles built for two: The palladium-catalyzed intermolecular tandem reaction of propargylic compounds with 2-iodophenols offers an efficient, direct route to spirocyclic compounds with high regioselectivity. The reaction conditions and the scope of the process are examined, and a possible mechanism is proposed.

KW - Cyclization

KW - Palladium

KW - Spiro compounds

KW - Tandem reactions

UR - https://www.scopus.com/pages/publications/34848888306

U2 - 10.1002/anie.200702238

DO - 10.1002/anie.200702238

M3 - 文章

AN - SCOPUS:34848888306

SN - 1433-7851

VL - 46

SP - 7068

EP - 7071

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 37

ER -

Highly regioselective synthesis of spirocyclic compounds by a palladium-catalyzed intermolecular tandem reaction

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this