Glomerular disease augments kidney accumulation of synthetic anionic polymers

Alexander N. Prossnitz; Gary W. Liu; Diana G. Eng; Yilong Cheng; Jeffrey W. Pippin; Robert J. Lamm; Chayanon Ngambenjawong; Stuart J. Shankland; Suzie H. Pun

doi:10.1016/j.biomaterials.2018.06.001

Glomerular disease augments kidney accumulation of synthetic anionic polymers

Alexander N. Prossnitz
, Gary W. Liu
, Diana G. Eng
, Yilong Cheng
, Jeffrey W. Pippin
, Robert J. Lamm
, Chayanon Ngambenjawong
, Stuart J. Shankland
, Suzie H. Pun

School of Chemistry

University of Washington

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

Statement of Purpose: Chronic kidney disease (CKD) affects over 30 million Americans. The majority of drugs that treat podocyte disease are administered systemically and have broad side effects. Since polymer-drug conjugates can alter the biodistribution and pharmokinetics of drug cargoes, we sought to elucidate the polymer properties that enhance in vivo kidney accumulation to enable new technologies to treat CKD.

Original language	English
Title of host publication	Society for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publication	The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
Publisher	Society for Biomaterials
Pages	504
Number of pages	1
ISBN (Electronic)	9781510883901
DOIs	https://doi.org/10.1016/j.biomaterials.2018.06.001
State	Published - 2019
Event	42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States Duration: 3 Apr 2019 → 6 Apr 2019

Publication series

Name	Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume	40
ISSN (Print)	1526-7547

Conference

Conference	42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Country/Territory	United States
City	Seattle
Period	3/04/19 → 6/04/19

Access to Document

10.1016/j.biomaterials.2018.06.001

Cite this

Prossnitz, A. N., Liu, G. W., Eng, D. G., Cheng, Y., Pippin, J. W., Lamm, R. J., Ngambenjawong, C., Shankland, S. J., & Pun, S. H. (2019). Glomerular disease augments kidney accumulation of synthetic anionic polymers. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (pp. 504). (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials. https://doi.org/10.1016/j.biomaterials.2018.06.001

Prossnitz, Alexander N. ; Liu, Gary W. ; Eng, Diana G. et al. / Glomerular disease augments kidney accumulation of synthetic anionic polymers. Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. pp. 504 (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).

@inproceedings{6bf164170c8c4702964fafb206e0f71b,

title = "Glomerular disease augments kidney accumulation of synthetic anionic polymers",

abstract = "Statement of Purpose: Chronic kidney disease (CKD) affects over 30 million Americans. The majority of drugs that treat podocyte disease are administered systemically and have broad side effects. Since polymer-drug conjugates can alter the biodistribution and pharmokinetics of drug cargoes, we sought to elucidate the polymer properties that enhance in vivo kidney accumulation to enable new technologies to treat CKD.",

author = "Prossnitz, \{Alexander N.\} and Liu, \{Gary W.\} and Eng, \{Diana G.\} and Yilong Cheng and Pippin, \{Jeffrey W.\} and Lamm, \{Robert J.\} and Chayanon Ngambenjawong and Shankland, \{Stuart J.\} and Pun, \{Suzie H.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Omnipress - All rights reserved.; 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence ; Conference date: 03-04-2019 Through 06-04-2019",

year = "2019",

doi = "10.1016/j.biomaterials.2018.06.001",

language = "英语",

series = "Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium",

publisher = "Society for Biomaterials",

pages = "504",

booktitle = "Society for Biomaterials Annual Meeting and Exposition 2019",

}

Prossnitz, AN, Liu, GW, Eng, DG, Cheng, Y, Pippin, JW, Lamm, RJ, Ngambenjawong, C, Shankland, SJ & Pun, SH 2019, Glomerular disease augments kidney accumulation of synthetic anionic polymers. in Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, vol. 40, Society for Biomaterials, pp. 504, 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence, Seattle, United States, 3/04/19. https://doi.org/10.1016/j.biomaterials.2018.06.001

Glomerular disease augments kidney accumulation of synthetic anionic polymers. / Prossnitz, Alexander N.; Liu, Gary W.; Eng, Diana G. et al.
Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. p. 504 (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Glomerular disease augments kidney accumulation of synthetic anionic polymers

AU - Prossnitz, Alexander N.

AU - Liu, Gary W.

AU - Eng, Diana G.

AU - Cheng, Yilong

AU - Pippin, Jeffrey W.

AU - Lamm, Robert J.

AU - Ngambenjawong, Chayanon

AU - Shankland, Stuart J.

AU - Pun, Suzie H.

PY - 2019

Y1 - 2019

N2 - Statement of Purpose: Chronic kidney disease (CKD) affects over 30 million Americans. The majority of drugs that treat podocyte disease are administered systemically and have broad side effects. Since polymer-drug conjugates can alter the biodistribution and pharmokinetics of drug cargoes, we sought to elucidate the polymer properties that enhance in vivo kidney accumulation to enable new technologies to treat CKD.

AB - Statement of Purpose: Chronic kidney disease (CKD) affects over 30 million Americans. The majority of drugs that treat podocyte disease are administered systemically and have broad side effects. Since polymer-drug conjugates can alter the biodistribution and pharmokinetics of drug cargoes, we sought to elucidate the polymer properties that enhance in vivo kidney accumulation to enable new technologies to treat CKD.

UR - https://www.scopus.com/pages/publications/85065436752

U2 - 10.1016/j.biomaterials.2018.06.001

DO - 10.1016/j.biomaterials.2018.06.001

M3 - 会议稿件

AN - SCOPUS:85065436752

T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium

SP - 504

BT - Society for Biomaterials Annual Meeting and Exposition 2019

PB - Society for Biomaterials

T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence

Y2 - 3 April 2019 through 6 April 2019

ER -

Prossnitz AN, Liu GW, Eng DG, Cheng Y, Pippin JW, Lamm RJ et al. Glomerular disease augments kidney accumulation of synthetic anionic polymers. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials. 2019. p. 504. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium). doi: 10.1016/j.biomaterials.2018.06.001

Glomerular disease augments kidney accumulation of synthetic anionic polymers

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