Genetic polymorphisms of 9 STR loci in Yugu ethnic group in Gansu Province

Yanjiong Chen; Teng Chen; Jianghua Lai; Haibo Zheng; Zhanhai Wang; Tianbo Jin; Shengbin Li

Genetic polymorphisms of 9 STR loci in Yugu ethnic group in Gansu Province

Yanjiong Chen
, Teng Chen
, Jianghua Lai
, Haibo Zheng
, Zhanhai Wang
, Tianbo Jin
, Shengbin Li

Health Science Center

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Objective: To study the STR genetic structure of Yugu ethnic group in Gansu Province. Methods: Distribution for nine STR loci was determined in a Chinese Yugu ethnic group based on STR genescan marked by fluorescence. Results: Sixty-five alleles and 178 genotypes were observed in 120 unrelated Chinese Yugu individuals, with the corresponding gene frequency and genotype frequency being 0. 0057 - 0. 5795 and 0.0114 - 0. 3068, respectively. The genotypes of nine STR loci were in accordance with the Hardy-Weinberg equilibrium (P>0.05). The statistical analysis of 9 STR loci showed PIC (polymorphism information content)≥ 0.6054, H (heterozygosity) ≥0. 6158, DP (discrimination power) ≥0. 8226, EPP (probabilities of paternity exclusion) ≥0. 5017. Conclusion: These results enrich the Chineses genetic database and play an important role in Chinese population genetic study and forensic medicine application.

Original language	English
Pages (from-to)	207-210
Number of pages	4
Journal	Journal of Xi'an Jiaotong University (Medical Sciences)
Volume	24
Issue number	3
State	Published - Jun 2003

Keywords

Genescan
Genetic polymorphism
STR
Yugu ethnic group

Cite this

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title = "Genetic polymorphisms of 9 STR loci in Yugu ethnic group in Gansu Province",

abstract = "Objective: To study the STR genetic structure of Yugu ethnic group in Gansu Province. Methods: Distribution for nine STR loci was determined in a Chinese Yugu ethnic group based on STR genescan marked by fluorescence. Results: Sixty-five alleles and 178 genotypes were observed in 120 unrelated Chinese Yugu individuals, with the corresponding gene frequency and genotype frequency being 0. 0057 - 0. 5795 and 0.0114 - 0. 3068, respectively. The genotypes of nine STR loci were in accordance with the Hardy-Weinberg equilibrium (P>0.05). The statistical analysis of 9 STR loci showed PIC (polymorphism information content)≥ 0.6054, H (heterozygosity) ≥0. 6158, DP (discrimination power) ≥0. 8226, EPP (probabilities of paternity exclusion) ≥0. 5017. Conclusion: These results enrich the Chineses genetic database and play an important role in Chinese population genetic study and forensic medicine application.",

keywords = "Genescan, Genetic polymorphism, STR, Yugu ethnic group",

author = "Yanjiong Chen and Teng Chen and Jianghua Lai and Haibo Zheng and Zhanhai Wang and Tianbo Jin and Shengbin Li",

year = "2003",

month = jun,

language = "英语",

volume = "24",

pages = "207--210",

journal = "Journal of Xi'an Jiaotong University (Medical Sciences)",

issn = "1671-8259",

publisher = "Xi'an Medical University",

number = "3",

}

TY - JOUR

T1 - Genetic polymorphisms of 9 STR loci in Yugu ethnic group in Gansu Province

AU - Chen, Yanjiong

AU - Chen, Teng

AU - Lai, Jianghua

AU - Zheng, Haibo

AU - Wang, Zhanhai

AU - Jin, Tianbo

AU - Li, Shengbin

PY - 2003/6

Y1 - 2003/6

N2 - Objective: To study the STR genetic structure of Yugu ethnic group in Gansu Province. Methods: Distribution for nine STR loci was determined in a Chinese Yugu ethnic group based on STR genescan marked by fluorescence. Results: Sixty-five alleles and 178 genotypes were observed in 120 unrelated Chinese Yugu individuals, with the corresponding gene frequency and genotype frequency being 0. 0057 - 0. 5795 and 0.0114 - 0. 3068, respectively. The genotypes of nine STR loci were in accordance with the Hardy-Weinberg equilibrium (P>0.05). The statistical analysis of 9 STR loci showed PIC (polymorphism information content)≥ 0.6054, H (heterozygosity) ≥0. 6158, DP (discrimination power) ≥0. 8226, EPP (probabilities of paternity exclusion) ≥0. 5017. Conclusion: These results enrich the Chineses genetic database and play an important role in Chinese population genetic study and forensic medicine application.

AB - Objective: To study the STR genetic structure of Yugu ethnic group in Gansu Province. Methods: Distribution for nine STR loci was determined in a Chinese Yugu ethnic group based on STR genescan marked by fluorescence. Results: Sixty-five alleles and 178 genotypes were observed in 120 unrelated Chinese Yugu individuals, with the corresponding gene frequency and genotype frequency being 0. 0057 - 0. 5795 and 0.0114 - 0. 3068, respectively. The genotypes of nine STR loci were in accordance with the Hardy-Weinberg equilibrium (P>0.05). The statistical analysis of 9 STR loci showed PIC (polymorphism information content)≥ 0.6054, H (heterozygosity) ≥0. 6158, DP (discrimination power) ≥0. 8226, EPP (probabilities of paternity exclusion) ≥0. 5017. Conclusion: These results enrich the Chineses genetic database and play an important role in Chinese population genetic study and forensic medicine application.

KW - Genescan

KW - Genetic polymorphism

KW - STR

KW - Yugu ethnic group

UR - https://www.scopus.com/pages/publications/0037898356

M3 - 文章

AN - SCOPUS:0037898356

SN - 1671-8259

VL - 24

SP - 207

EP - 210

JO - Journal of Xi'an Jiaotong University (Medical Sciences)

JF - Journal of Xi'an Jiaotong University (Medical Sciences)

IS - 3

ER -

Genetic polymorphisms of 9 STR loci in Yugu ethnic group in Gansu Province

Abstract

Keywords

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