Abstract
Objective: To obtained the genetic polymorphism of Y chromosomal short tandem repeat (Y-STR) loci in Ningxia Hui population. Methods: Blood samples were collected from 150 unrelated healthy male individuals of Ningxia Hui ethnic group. Twelve Y-STR loci were amplified in one tube by using the PowerPlex® Y System STR Amplification Kit, and the genotypes were determined using Genescan and Genotype software of ABI377 DNA sequencer and the frequency of alleles and haplotypes of Ningxia Hui ethnic was obtained. Results: Seventy-five alleles were observed at 12 Y-STR loci. The frequency ranged from 0.0067-0.7067 and the gene diversity ranged from 0.4446-0.8877. Totally 148 different haplotypes were found, which were unique in 150 males. Two haplotypes were shared by 2 males respectively. The haplotype diversity was 0.9864. Conclusion: The 12 Y-STR loci are highly polymorphic in Ningxia Hui population and are suitable for genetics and forensic research.
| Original language | English |
|---|---|
| Pages (from-to) | 594-597 |
| Number of pages | 4 |
| Journal | Chinese Journal of Medical Genetics |
| Volume | 24 |
| Issue number | 5 |
| State | Published - 10 Oct 2007 |
Keywords
- Genetic polymorphism
- Hui ethnic group
- Y chromosomal short tandem repeat
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