Abstract
Objective: To study the protein and lipid in the membrane of gastric cancer tissues and normal tissues with Fourier transform infrared (FTIR) and explore the special spectral features of the membrane of gastric cancer tissues compared with the membrane of normal tissues, cancer cells and cancer tissues. Methods: We extracted membrane from cancer tissue and normal tissue samples, sheeted them with KBr, observed them by FTIR and compared the spectral data of the membrane of gastric cancer tissues, the membrane of normal tissues, cancer cells and cancer tissues. Results: Both similarities and differences were found in the infrared spectral features between the membranes of gastric cancer tissues and normal tissues. The spectral features of the membrane of gastric cancer tissues had similarities and differences with those of gastric tissues and grastric cell strain, which were shown in the changes of the 2957, 2927, 2853 and 1740 cm"1 bands related to lipids. Conclusion: The results suggest that the spectral features of the membrane of gastric cancer tissues are significantly different from those of the membrane of normal tissues, cancer cells and cancer tissues, which has enriched studies on biological tissues infrared spectroscopy.
| Original language | English |
|---|---|
| Pages (from-to) | 463-465 |
| Number of pages | 3 |
| Journal | Journal of Xi'an Jiaotong University (Medical Sciences) |
| Volume | 30 |
| Issue number | 4 |
| State | Published - 2009 |
Keywords
- Gastric cancer
- Infrared spectrum
- Membrane
- Membrane lipid
- Membrane protein
