Abstract
Development of novel biomaterials for bone regeneration is based on the sufficient bone-bonding ability, bioactivity and biocompatibility. In this study, novel flexible poly(butylene succinate)/polydimethysiloxane-modified bioactive glass/nano-hydroxyapatite (PBSu/PDMS-BG/nHA) hybrid bioceramic with various nHA concentration on the in vitro bone-like hydroxyapatite (HA) formation, biomineralization activity and osteoblast cell biocompatibility were investigated. The rapid precipitation of HA on the hybrid bioceramic surfaces was found after being immersed in simulated body fluid (SBF) for seven days. Results show that the amount of HA deposition increased with the increase of nHA concentration. The optimized PBSu/PDMS-BG/nHA hybrid bioceramic exhibited good flexibility, high biomineralization activity and good osteoblast cell biocompatibility.
| Original language | English |
|---|---|
| Article number | 2050013 |
| Journal | Journal of Advanced Dielectrics |
| Volume | 10 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1 Aug 2020 |
Keywords
- Sol-gel process
- biomineralization activity
- cell biocompatibility
- hybrid bioceramic
- nano-hydroxyapatite
Fingerprint
Dive into the research topics of 'Flexible organic-inorganic hybrid bioceramic for bone tissue regeneration'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver