FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population

Peng Xia; Bin Li; Tingting Geng; Zhiping Deng; Chengxue Dang; Dongmin Chang; Longli Kang; Tianbo Jin; Chao Chen

FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population

Peng Xia
, Bin Li
, Tingting Geng
, Zhiping Deng
, Chengxue Dang
, Dongmin Chang
, Longli Kang
, Tianbo Jin
, Chao Chen

Health Science Center

Xi'an Jiaotong University
Northwest University China
National Engineering Research Center for Miniaturized Detection Systems
Xi'an Medical University
Xizang Minzu University
Yale University

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Aims and background: Breast cancer is one of the most common neoplasms among women in many developing countries including China, and is the leading cause of female cancer-related deaths worldwide. Methods: In the current study, we analyzed the relationship between 14 tag single-nucleotide polymorphisms (tSNPs) and breast cancer risk in the Han Chinese population including 185 breast cancer patients and 199 healthy women controls on the different types of breast cancer and menopausal status. Results: Overall, we found rs2981579 in the FGFR2 gene, and rs2380205 were associated with breast cancer susceptibility.

Original language	English
Pages (from-to)	1854-1861
Number of pages	8
Journal	American Journal of Cancer Research
Volume	5
Issue number	5
State	Published - 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Breast cancer
Case-control studies
FGFR2
Single nucleotide polymorphism (SNP)

Cite this

@article{f06db6de23f6471982da5da831a82bc8,

title = "FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population",

abstract = "Aims and background: Breast cancer is one of the most common neoplasms among women in many developing countries including China, and is the leading cause of female cancer-related deaths worldwide. Methods: In the current study, we analyzed the relationship between 14 tag single-nucleotide polymorphisms (tSNPs) and breast cancer risk in the Han Chinese population including 185 breast cancer patients and 199 healthy women controls on the different types of breast cancer and menopausal status. Results: Overall, we found rs2981579 in the FGFR2 gene, and rs2380205 were associated with breast cancer susceptibility.",

keywords = "Breast cancer, Case-control studies, FGFR2, Single nucleotide polymorphism (SNP)",

author = "Peng Xia and Bin Li and Tingting Geng and Zhiping Deng and Chengxue Dang and Dongmin Chang and Longli Kang and Tianbo Jin and Chao Chen",

year = "2015",

language = "英语",

volume = "5",

pages = "1854--1861",

journal = "American Journal of Cancer Research",

issn = "2156-6976",

publisher = "E-Century Publishing Corporation",

number = "5",

}

TY - JOUR

T1 - FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population

AU - Xia, Peng

AU - Li, Bin

AU - Geng, Tingting

AU - Deng, Zhiping

AU - Dang, Chengxue

AU - Chang, Dongmin

AU - Kang, Longli

AU - Jin, Tianbo

AU - Chen, Chao

PY - 2015

Y1 - 2015

N2 - Aims and background: Breast cancer is one of the most common neoplasms among women in many developing countries including China, and is the leading cause of female cancer-related deaths worldwide. Methods: In the current study, we analyzed the relationship between 14 tag single-nucleotide polymorphisms (tSNPs) and breast cancer risk in the Han Chinese population including 185 breast cancer patients and 199 healthy women controls on the different types of breast cancer and menopausal status. Results: Overall, we found rs2981579 in the FGFR2 gene, and rs2380205 were associated with breast cancer susceptibility.

AB - Aims and background: Breast cancer is one of the most common neoplasms among women in many developing countries including China, and is the leading cause of female cancer-related deaths worldwide. Methods: In the current study, we analyzed the relationship between 14 tag single-nucleotide polymorphisms (tSNPs) and breast cancer risk in the Han Chinese population including 185 breast cancer patients and 199 healthy women controls on the different types of breast cancer and menopausal status. Results: Overall, we found rs2981579 in the FGFR2 gene, and rs2380205 were associated with breast cancer susceptibility.

KW - Breast cancer

KW - Case-control studies

KW - FGFR2

KW - Single nucleotide polymorphism (SNP)

UR - https://www.scopus.com/pages/publications/85006197369

M3 - 文章

AN - SCOPUS:85006197369

SN - 2156-6976

VL - 5

SP - 1854

EP - 1861

JO - American Journal of Cancer Research

JF - American Journal of Cancer Research

IS - 5

ER -

FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population

Abstract

UN SDGs

Keywords

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